Milk proteins, peptides, and oligosaccharides: Effects against the 21st century disorders

Chia Chien Hsieh, Blanca Hernández-Ledesma, Samuel Fernández-Tomé, Valerie Weinborn, Daniela Barile, Juliana María Leite Nobrega De Moura Bell

Research output: Contribution to journalReview article

36 Citations (Scopus)

Abstract

Milk is the most complete food for mammals, as it supplies all the energy and nutrients needed for the proper growth and development of the neonate. Milk is a source of many bioactive components, which not only help meeting the nutritional requirements of the consumers, but also play a relevant role in preventing various disorders. Milk-derived proteins and peptides have the potential to act as coadjuvants in conventional therapies, addressing cardiovascular diseases, metabolic disorders, intestinal health, and chemopreventive properties. In addition to being a source of proteins and peptides, milk contains complex oligosaccharides that possess important functions related to the newborn's development and health. Some of the health benefits attributed to milk oligosaccharides include prebiotic probifidogenic effects, antiadherence of pathogenic bacteria, and immunomodulation. This review focuses on recent findings demonstrating the biological activities of milk peptides, proteins, and oligosaccharides towards the prevention of diseases of the 21st century. Processing challenges hindering large-scale production and commercialization of those bioactive compounds have been also addressed.

Original languageEnglish
Article number146840
JournalBioMed Research International
Volume2015
DOIs
Publication statusPublished - 2015 Jan 1

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ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)
  • Immunology and Microbiology(all)

Cite this

Hsieh, C. C., Hernández-Ledesma, B., Fernández-Tomé, S., Weinborn, V., Barile, D., & De Moura Bell, J. M. L. N. (2015). Milk proteins, peptides, and oligosaccharides: Effects against the 21st century disorders. BioMed Research International, 2015, [146840]. https://doi.org/10.1155/2015/146840