Magnetic resonance imaging of hyperpolarized 3He Detected With a High-Tc SQUID in microtesla magnetic field at laboratory environment fields

Hsin Hsien Chen*, Hong Chang Yang, Herng Er Horng, S. H. Liao, Shieh Yueh Yang, K. L. Chen, L. M. Wang, M. J. Chen

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

4 Citations (Scopus)


Nuclear magnetic resonance and imaging (NMR/MRI) of optically pumped (OP) hyperpolarized 3He were studied by using a high-c SQUID magnetometer device in microtesla magnetic fields. The OP cell was filled with a few milligrams of Rb metal, 0.0798 bar N2 gas and 0.705 bar 3He gas. The 3He cell had been hyperpolarized at an optical pumping system for 5 ∼ hours first; then it was moved to the SQUID-detected nuclear magnetic resonance and imaging system to measure. An appropriate B1 pulse level and time duration generated a 5° low flip angle of polarization. The free induction decay NMR signals were measured. The spin-lattice relaxation time (T1) of 3He was 4.7 hours.We improved the line width of NMR spectrum to 0.8 Hz by compensating the inhomogeneous gradient field of environment. The filtered back projection image of hyperpolarized 3He could show a clear image in one shot. The SQUID-detected NMR/MRI would be a great interest for biological imaging.

Original languageEnglish
Article number5621847
Pages (from-to)505-508
Number of pages4
JournalIEEE Transactions on Applied Superconductivity
Issue number3 PART 1
Publication statusPublished - 2011 Jun
Externally publishedYes


  • Flux coupling
  • Hyperpolarized gas

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Condensed Matter Physics
  • Electrical and Electronic Engineering


Dive into the research topics of 'Magnetic resonance imaging of hyperpolarized <sup>3</sup>He Detected With a High-T<sub>c</sub> SQUID in microtesla magnetic field at laboratory environment fields'. Together they form a unique fingerprint.

Cite this