半導體螢光奈米粒子在生物上的應用

Translated title of the contribution: Luminescent Nanocrystals for Biological Detection and Imaging

楊 正義, 吳 仁家, 陳 家俊(Chia-Chun Chen), 胡 焯淳

Research output: Contribution to journalArticlepeer-review

Abstract

Recent advances in nanomaterials have produced a new class of fluorescent labels by conjugating semiconductor nanocrystals with biorecognition molecules. These nanometer-sized conjugates are water-soluble and biocompatible, and provide important advantages over organic dyes and lanthanide probes. In particular, the emission wavelength of luminescent nanocrystals can be continuously tuned by changing the particle size, and a single light source can be used for simultaneous excitation of all different-sized dots. High-quality dots are also highly stable against photobleaching and have narrow, symmetric emission spectra. These novel optical properties render quantum dots ideal fluorophores for ultrasensitive, multicolor, and multiplexing applications in molecular biotechnology and bioengineering.
Translated title of the contributionLuminescent Nanocrystals for Biological Detection and Imaging
Original languageChinese (Traditional)
Pages (from-to)35-47
Number of pages13
Journal光學工程
Issue number83
Publication statusPublished - 2003

Keywords

  • fluorescent
  • nanocrystal
  • image

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