Iron/acetic acid mediated intermolecular tandem C-C and C-N bond formation: An easy access to acridinone and quinoline derivatives

R. R. Rajawinslin; Sachin D. Gawande; Veerababurao Kavala; Yi Hsiang Huang; Chun Wei Kuo; Ting Shen Kuo; Mei Ling Chen; Chiu Hui He; Ching Fa Yao

doi:10.1039/c4ra06410k

Iron/acetic acid mediated intermolecular tandem C-C and C-N bond formation: An easy access to acridinone and quinoline derivatives

R. R. Rajawinslin, Sachin D. Gawande, Veerababurao Kavala, Yi Hsiang Huang, Chun Wei Kuo, Ting Shen Kuo, Mei Ling Chen, Chiu Hui He, Ching Fa Yao^*

^*Corresponding author for this work

Department of Chemistry

Research output: Contribution to journal › Article › peer-review

36 Citations (Scopus)

Abstract

An efficient iron/acetic acid mediated one pot reductive cyclization protocol was successfully developed for the synthesis of acridinone and quinoline derivatives. This highly efficient process proceeds under mild conditions, tolerates different functional groups, and provides various substituted acridinone and quinoline derivatives in good to excellent yields. In addition, biologically active compounds also accessed from this method.

Original language	English
Pages (from-to)	37806-37811
Number of pages	6
Journal	RSC Advances
Volume	4
Issue number	71
DOIs	https://doi.org/10.1039/c4ra06410k
Publication status	Published - 2014

ASJC Scopus subject areas

General Chemistry
General Chemical Engineering

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10.1039/c4ra06410k

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title = "Iron/acetic acid mediated intermolecular tandem C-C and C-N bond formation: An easy access to acridinone and quinoline derivatives",

abstract = "An efficient iron/acetic acid mediated one pot reductive cyclization protocol was successfully developed for the synthesis of acridinone and quinoline derivatives. This highly efficient process proceeds under mild conditions, tolerates different functional groups, and provides various substituted acridinone and quinoline derivatives in good to excellent yields. In addition, biologically active compounds also accessed from this method.",

author = "Rajawinslin, {R. R.} and Gawande, {Sachin D.} and Veerababurao Kavala and Huang, {Yi Hsiang} and Kuo, {Chun Wei} and Kuo, {Ting Shen} and Chen, {Mei Ling} and He, {Chiu Hui} and Yao, {Ching Fa}",

year = "2014",

doi = "10.1039/c4ra06410k",

language = "English",

volume = "4",

pages = "37806--37811",

journal = "RSC Advances",

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publisher = "Royal Society of Chemistry",

number = "71",

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T1 - Iron/acetic acid mediated intermolecular tandem C-C and C-N bond formation

T2 - An easy access to acridinone and quinoline derivatives

AU - Rajawinslin, R. R.

AU - Gawande, Sachin D.

AU - Kavala, Veerababurao

AU - Huang, Yi Hsiang

AU - Kuo, Chun Wei

AU - Kuo, Ting Shen

AU - Chen, Mei Ling

AU - He, Chiu Hui

AU - Yao, Ching Fa

PY - 2014

Y1 - 2014

N2 - An efficient iron/acetic acid mediated one pot reductive cyclization protocol was successfully developed for the synthesis of acridinone and quinoline derivatives. This highly efficient process proceeds under mild conditions, tolerates different functional groups, and provides various substituted acridinone and quinoline derivatives in good to excellent yields. In addition, biologically active compounds also accessed from this method.

AB - An efficient iron/acetic acid mediated one pot reductive cyclization protocol was successfully developed for the synthesis of acridinone and quinoline derivatives. This highly efficient process proceeds under mild conditions, tolerates different functional groups, and provides various substituted acridinone and quinoline derivatives in good to excellent yields. In addition, biologically active compounds also accessed from this method.

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UR - http://www.scopus.com/inward/citedby.url?scp=84906861565&partnerID=8YFLogxK

U2 - 10.1039/c4ra06410k

DO - 10.1039/c4ra06410k

M3 - Article

AN - SCOPUS:84906861565

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SP - 37806

EP - 37811

JO - RSC Advances

JF - RSC Advances

IS - 71

ER -

Iron/acetic acid mediated intermolecular tandem C-C and C-N bond formation: An easy access to acridinone and quinoline derivatives

Abstract

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CCDC 998616: Experimental Crystal Structure Determination

CCDC 998615: Experimental Crystal Structure Determination

CCDC 998617: Experimental Crystal Structure Determination

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Iron/acetic acid mediated intermolecular tandem C-C and C-N bond formation: An easy access to acridinone and quinoline derivatives

Abstract

ASJC Scopus subject areas

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Datasets

CCDC 998616: Experimental Crystal Structure Determination

CCDC 998615: Experimental Crystal Structure Determination

CCDC 998617: Experimental Crystal Structure Determination

Cite this