Iron/acetic acid mediated intermolecular tandem C-C and C-N bond formation: An easy access to acridinone and quinoline derivatives

R. R. Rajawinslin, Sachin D. Gawande, Veerababurao Kavala, Yi Hsiang Huang, Chun Wei Kuo, Ting Shen Kuo, Mei Ling Chen, Chiu Hui He, Ching Fa Yao

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Abstract

An efficient iron/acetic acid mediated one pot reductive cyclization protocol was successfully developed for the synthesis of acridinone and quinoline derivatives. This highly efficient process proceeds under mild conditions, tolerates different functional groups, and provides various substituted acridinone and quinoline derivatives in good to excellent yields. In addition, biologically active compounds also accessed from this method.

Original languageEnglish
Pages (from-to)37806-37811
Number of pages6
JournalRSC Advances
Volume4
Issue number71
DOIs
Publication statusPublished - 2014 Jan 1

ASJC Scopus subject areas

  • Chemistry(all)
  • Chemical Engineering(all)

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    Rajawinslin, R. R., Gawande, S. D., Kavala, V., Huang, Y. H., Kuo, C. W., Kuo, T. S., Chen, M. L., He, C. H., & Yao, C. F. (2014). Iron/acetic acid mediated intermolecular tandem C-C and C-N bond formation: An easy access to acridinone and quinoline derivatives. RSC Advances, 4(71), 37806-37811. https://doi.org/10.1039/c4ra06410k