Iron/acetic acid mediated intermolecular tandem C-C and C-N bond formation: An easy access to acridinone and quinoline derivatives

R. R. Rajawinslin; Sachin D. Gawande; Veerababurao Kavala; Yi Hsiang Huang; Chun Wei Kuo; Ting Shen Kuo; Mei Ling Chen; Chiu Hui He; Ching Fa Yao

doi:10.1039/c4ra06410k

Iron/acetic acid mediated intermolecular tandem C-C and C-N bond formation: An easy access to acridinone and quinoline derivatives

R. R. Rajawinslin, Sachin D. Gawande, Veerababurao Kavala, Yi Hsiang Huang, Chun Wei Kuo, Ting Shen Kuo, Mei Ling Chen, Chiu Hui He, Ching Fa Yao

Department of Chemistry

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23 Citations (Scopus)

Abstract

An efficient iron/acetic acid mediated one pot reductive cyclization protocol was successfully developed for the synthesis of acridinone and quinoline derivatives. This highly efficient process proceeds under mild conditions, tolerates different functional groups, and provides various substituted acridinone and quinoline derivatives in good to excellent yields. In addition, biologically active compounds also accessed from this method.

Original language	English
Pages (from-to)	37806-37811
Number of pages	6
Journal	RSC Advances
Volume	4
Issue number	71
DOIs	https://doi.org/10.1039/c4ra06410k
Publication status	Published - 2014 Jan 1

ASJC Scopus subject areas

Chemistry(all)
Chemical Engineering(all)

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10.1039/c4ra06410k

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Iron/acetic acid mediated intermolecular tandem C-C and C-N bond formation : An easy access to acridinone and quinoline derivatives. / Rajawinslin, R. R.; Gawande, Sachin D.; Kavala, Veerababurao; Huang, Yi Hsiang; Kuo, Chun Wei; Kuo, Ting Shen; Chen, Mei Ling; He, Chiu Hui; Yao, Ching Fa.

In: RSC Advances, Vol. 4, No. 71, 01.01.2014, p. 37806-37811.

Research output: Contribution to journal › Article › peer-review

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abstract = "An efficient iron/acetic acid mediated one pot reductive cyclization protocol was successfully developed for the synthesis of acridinone and quinoline derivatives. This highly efficient process proceeds under mild conditions, tolerates different functional groups, and provides various substituted acridinone and quinoline derivatives in good to excellent yields. In addition, biologically active compounds also accessed from this method.",

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AU - Rajawinslin, R. R.

AU - Gawande, Sachin D.

AU - Kavala, Veerababurao

AU - Huang, Yi Hsiang

AU - Kuo, Chun Wei

AU - Kuo, Ting Shen

AU - Chen, Mei Ling

AU - He, Chiu Hui

AU - Yao, Ching Fa

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AB - An efficient iron/acetic acid mediated one pot reductive cyclization protocol was successfully developed for the synthesis of acridinone and quinoline derivatives. This highly efficient process proceeds under mild conditions, tolerates different functional groups, and provides various substituted acridinone and quinoline derivatives in good to excellent yields. In addition, biologically active compounds also accessed from this method.

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Iron/acetic acid mediated intermolecular tandem C-C and C-N bond formation: An easy access to acridinone and quinoline derivatives

Abstract

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