Iodine catalyzed one-pot synthesis of flavanone and tetrahydropyrimidine derivatives via Mannich type reaction

Veerababurao Kavala, Chunchi Lin, Chun Wei Kuo, Hulin Fang, Ching Fa Yao

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39 Citations (Scopus)

Abstract

A variety of functionalized flavanone derivatives and tetrahydropyrimidine derivatives were achieved under remarkably mild conditions. The combination of good to excellent yields, a simple work-up, and the high compatibility of functional groups makes this an attractive synthetic approach to access flavanone and tetrahydropyrimidine derivatives.

Original languageEnglish
Pages (from-to)1321-1329
Number of pages9
JournalTetrahedron
Volume68
Issue number4
DOIs
Publication statusPublished - 2012 Jan 28

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Keywords

  • Flavanones
  • Iodine
  • Mannich reaction
  • Tetrahydropyrimidine

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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