Iodine catalyzed one-pot synthesis of flavanone and tetrahydropyrimidine derivatives via Mannich type reaction

Veerababurao Kavala, Chunchi Lin, Chun Wei Kuo, Hulin Fang, Ching-Fa Yao

Research output: Contribution to journal › Article

37 Citations (Scopus)

Abstract

A variety of functionalized flavanone derivatives and tetrahydropyrimidine derivatives were achieved under remarkably mild conditions. The combination of good to excellent yields, a simple work-up, and the high compatibility of functional groups makes this an attractive synthetic approach to access flavanone and tetrahydropyrimidine derivatives.

Original languageEnglish
Pages (from-to)1321-1329
Number of pages9
JournalTetrahedron
Volume68
Issue number4
DOIs
Publication statusPublished - 2012 Jan 28

Fingerprint

Iodine
Derivatives
Functional groups
flavanone

Keywords

  • Flavanones
  • Iodine
  • Mannich reaction
  • Tetrahydropyrimidine

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

Cite this

Iodine catalyzed one-pot synthesis of flavanone and tetrahydropyrimidine derivatives via Mannich type reaction. / Kavala, Veerababurao; Lin, Chunchi; Kuo, Chun Wei; Fang, Hulin; Yao, Ching-Fa.

In: Tetrahedron, Vol. 68, No. 4, 28.01.2012, p. 1321-1329.

Research output: Contribution to journal › Article

Kavala, V, Lin, C, Kuo, CW, Fang, H & Yao, C-F 2012, 'Iodine catalyzed one-pot synthesis of flavanone and tetrahydropyrimidine derivatives via Mannich type reaction', Tetrahedron, vol. 68, no. 4, pp. 1321-1329. https://doi.org/10.1016/j.tet.2011.11.022
Kavala V, Lin C, Kuo CW, Fang H, Yao C-F. Iodine catalyzed one-pot synthesis of flavanone and tetrahydropyrimidine derivatives via Mannich type reaction. Tetrahedron. 2012 Jan 28;68(4):1321-1329. https://doi.org/10.1016/j.tet.2011.11.022
Kavala, Veerababurao ; Lin, Chunchi ; Kuo, Chun Wei ; Fang, Hulin ; Yao, Ching-Fa. / Iodine catalyzed one-pot synthesis of flavanone and tetrahydropyrimidine derivatives via Mannich type reaction. In: Tetrahedron. 2012 ; Vol. 68, No. 4. pp. 1321-1329.
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