Improvement of quality of life in methadone treatment patients in northern Taiwan: A follow-up study

Ying Chun Chou, Shu Fang Shih, Wei Der Tsai, Chiang shan R. Li, Ke Xu, Tony Szu Hsien Lee*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

29 Citations (Scopus)


Background: This study examined long-term improvement of quality of life amongst heroin users enrolled in methadone maintenance treatment (MMT).Methods: The sample contained 553 heroin-dependent individuals from 4 hospitals in northern Taiwan who enrolled in MMT for an average of 184 days. Each patient signed a consent form and was assessed prospectively 3 times semi-annually. Quality of life was measured using the WHOQOL-BREF questionnaire, 26 items of which were scored by the participants. The WHOQOL-BREF consists of four domains: physical, psychological, social, and environmental. 285 and 155 participants completed 6-month and 12-month follow-ups respectively.Results: After controlling for demographic and clinical characteristics, there were statistically significant improvements in the psychological and environmental domains between baseline and 6 months. Significant improvements were found in psychological and social domains between baseline and 12 months.Conclusions: It is concluded that methadone maintenance treatment improves heroin users' long-term quality of life in the psychological and social relationship domains.

Original languageEnglish
Article number190
JournalBMC Psychiatry
Publication statusPublished - 2013 Jul 16


  • Effectiveness
  • Heroin users
  • Methadone maintenance treatment
  • Quality of life

ASJC Scopus subject areas

  • Psychiatry and Mental health


Dive into the research topics of 'Improvement of quality of life in methadone treatment patients in northern Taiwan: A follow-up study'. Together they form a unique fingerprint.

Cite this