Immunomagnetical reduction using high T c superconducting quantum interference device (SQUID)

J. J. Chieh; C. H. Chen; Shieh-Yueh Yang; Herng-Er Horng; Hong-Chang Yang; Chin Yih Hong

doi:10.1109/BIBE.2009.81

Immunomagnetical reduction using high T _c superconducting quantum interference device (SQUID)

J. J. Chieh, C. H. Chen, Shieh-Yueh Yang, Herng-Er Horng, Hong-Chang Yang, Chin Yih Hong

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

1 Citation (Scopus)

Abstract

In this work, we develop a platform for assaying biomolecules involving the measurement of alternating current ac magnetoreduction of magnetic reagent mixed with a detected sample. The magnetic reagent contains magnetic nanoparticles coated with a given kind of antibody, which associates with conjugated biomolecules. Then, the biomolecules can be quantitatively detected by measuring the ac magnetoreduction of magnetic reagent. To achieve hyper-high-sensitivity assay, a system utilizing a high-transition-temperature rf superconducting quantum interference device (SQUID) as a sensor to probe the magnetoreduction of reagent due to the association between biomolecules and magnetic nanoparticles. Examples to assay human CRP are given to demonstrate the validity of the assay platform, as well as the hyper-high sensitivity.

Original language	English
Title of host publication	Proceedings of the 2009 9th IEEE International Conference on Bioinformatics and BioEngineering, BIBE 2009
Pages	364-365
Number of pages	2
DOIs	https://doi.org/10.1109/BIBE.2009.81
Publication status	Published - 2009
Event	2009 9th IEEE International Conference on Bioinformatics and BioEngineering, BIBE 2009 - Taichung, Taiwan Duration: 2009 Jun 22 → 2009 Jun 24

Publication series

Name	Proceedings of the 2009 9th IEEE International Conference on Bioinformatics and BioEngineering, BIBE 2009

Other

Other	2009 9th IEEE International Conference on Bioinformatics and BioEngineering, BIBE 2009
Country/Territory	Taiwan
City	Taichung
Period	2009/06/22 → 2009/06/24

Keywords

Ac magnetoreduction
Magnetic nanoparticles
SQUID

ASJC Scopus subject areas

Information Systems
Biomedical Engineering
Health Informatics

Access to Document

10.1109/BIBE.2009.81

Cite this

Chieh, J. J., Chen, C. H., Yang, S-Y., Horng, H-E., Yang, H-C., & Hong, C. Y. (2009). Immunomagnetical reduction using high T _c superconducting quantum interference device (SQUID). In Proceedings of the 2009 9th IEEE International Conference on Bioinformatics and BioEngineering, BIBE 2009 (pp. 364-365). Article 5211243 (Proceedings of the 2009 9th IEEE International Conference on Bioinformatics and BioEngineering, BIBE 2009). https://doi.org/10.1109/BIBE.2009.81

Immunomagnetical reduction using high T _c superconducting quantum interference device (SQUID). / Chieh, J. J.; Chen, C. H.; Yang, Shieh-Yueh et al.
Proceedings of the 2009 9th IEEE International Conference on Bioinformatics and BioEngineering, BIBE 2009. 2009. p. 364-365 5211243 (Proceedings of the 2009 9th IEEE International Conference on Bioinformatics and BioEngineering, BIBE 2009).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Chieh, JJ, Chen, CH, Yang, S-Y, Horng, H-E, Yang, H-C & Hong, CY 2009, Immunomagnetical reduction using high T _c superconducting quantum interference device (SQUID). in Proceedings of the 2009 9th IEEE International Conference on Bioinformatics and BioEngineering, BIBE 2009., 5211243, Proceedings of the 2009 9th IEEE International Conference on Bioinformatics and BioEngineering, BIBE 2009, pp. 364-365, 2009 9th IEEE International Conference on Bioinformatics and BioEngineering, BIBE 2009, Taichung, Taiwan, 2009/06/22. https://doi.org/10.1109/BIBE.2009.81

Chieh JJ, Chen CH, Yang S-Y, Horng H-E, Yang H-C, Hong CY. Immunomagnetical reduction using high T _c superconducting quantum interference device (SQUID). In Proceedings of the 2009 9th IEEE International Conference on Bioinformatics and BioEngineering, BIBE 2009. 2009. p. 364-365. 5211243. (Proceedings of the 2009 9th IEEE International Conference on Bioinformatics and BioEngineering, BIBE 2009). doi: 10.1109/BIBE.2009.81

Chieh, J. J. ; Chen, C. H. ; Yang, Shieh-Yueh et al. / Immunomagnetical reduction using high T _c superconducting quantum interference device (SQUID). Proceedings of the 2009 9th IEEE International Conference on Bioinformatics and BioEngineering, BIBE 2009. 2009. pp. 364-365 (Proceedings of the 2009 9th IEEE International Conference on Bioinformatics and BioEngineering, BIBE 2009).

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