Immunomagnetical reduction using high T c superconducting quantum interference device (SQUID)

J. J. Chieh, C. H. Chen, S. Y. Yang, H. E. Horng, H. C. Yang, Chin Yih Hong

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Citation (Scopus)

Abstract

In this work, we develop a platform for assaying biomolecules involving the measurement of alternating current ac magnetoreduction of magnetic reagent mixed with a detected sample. The magnetic reagent contains magnetic nanoparticles coated with a given kind of antibody, which associates with conjugated biomolecules. Then, the biomolecules can be quantitatively detected by measuring the ac magnetoreduction of magnetic reagent. To achieve hyper-high-sensitivity assay, a system utilizing a high-transition-temperature rf superconducting quantum interference device (SQUID) as a sensor to probe the magnetoreduction of reagent due to the association between biomolecules and magnetic nanoparticles. Examples to assay human CRP are given to demonstrate the validity of the assay platform, as well as the hyper-high sensitivity.

Original languageEnglish
Title of host publicationProceedings of the 2009 9th IEEE International Conference on Bioinformatics and BioEngineering, BIBE 2009
Pages364-365
Number of pages2
DOIs
Publication statusPublished - 2009 Nov 18
Event2009 9th IEEE International Conference on Bioinformatics and BioEngineering, BIBE 2009 - Taichung, Taiwan
Duration: 2009 Jun 222009 Jun 24

Publication series

NameProceedings of the 2009 9th IEEE International Conference on Bioinformatics and BioEngineering, BIBE 2009

Other

Other2009 9th IEEE International Conference on Bioinformatics and BioEngineering, BIBE 2009
CountryTaiwan
CityTaichung
Period09/6/2209/6/24

Keywords

  • Ac magnetoreduction
  • Magnetic nanoparticles
  • SQUID

ASJC Scopus subject areas

  • Information Systems
  • Biomedical Engineering
  • Health Informatics

Fingerprint Dive into the research topics of 'Immunomagnetical reduction using high T <sub>c</sub> superconducting quantum interference device (SQUID)'. Together they form a unique fingerprint.

  • Cite this

    Chieh, J. J., Chen, C. H., Yang, S. Y., Horng, H. E., Yang, H. C., & Hong, C. Y. (2009). Immunomagnetical reduction using high T c superconducting quantum interference device (SQUID). In Proceedings of the 2009 9th IEEE International Conference on Bioinformatics and BioEngineering, BIBE 2009 (pp. 364-365). [5211243] (Proceedings of the 2009 9th IEEE International Conference on Bioinformatics and BioEngineering, BIBE 2009). https://doi.org/10.1109/BIBE.2009.81