Imaging of Magnetic Nanoparticles Using a Second Harmonic of Magnetization With DC Bias Field

Saburo Tanaka, Hayaki Murata, Tomoya Oishi, Yoshimi Hatsukade, Yi Zhang, Herng Er Horng, Shu Hsien Liao, Hong Chang Yang

    Research output: Contribution to journalArticle

    14 Citations (Scopus)

    Abstract

    We have developed a method to improve the detection sensitivity for the magnetization M of magnetic nanoparticles (MNPs) using a high Tc superconducting quantum interference device magnetometer. The M response of MNP to an applied magnetic field H(M-H characteristics) can be divided into a linear region and a saturation region, which are separated at a transition point Hk. When applying an excitation ac magnetic field (Hac) and an additional dc bias field Hdc = Hk, the second harmonic of M reaches a maximum due to the nonlinearity of its M - H characteristics. This harmonic is stronger than any other harmonics, including a third harmonic. The advantage of using the second harmonic response is that the response can be measured even in a small field Hac. The M response of MNP was systematically analyzed and experimentally demonstrated. For conventional detection using a third harmonic, the amplitude of the Hac must be larger than the threshold level, which is almost the same as Hk. Detection methods using a second harmonic can be applied to magnetic particle imaging. We finally demonstrate the construction of a 1-D image of two separated bottle-shaped MNP samples using the method with a lock-in amplifier.

    Original languageEnglish
    Article number6502504
    Number of pages1
    JournalIEEE Transactions on Magnetics
    Volume51
    Issue number2
    DOIs
    Publication statusPublished - 2015 Feb 1

    Fingerprint

    Magnetization
    Nanoparticles
    Imaging techniques
    Magnetic fields
    SQUIDs
    Bottles
    Magnetometers

    ASJC Scopus subject areas

    • Electronic, Optical and Magnetic Materials
    • Electrical and Electronic Engineering

    Cite this

    Imaging of Magnetic Nanoparticles Using a Second Harmonic of Magnetization With DC Bias Field. / Tanaka, Saburo; Murata, Hayaki; Oishi, Tomoya; Hatsukade, Yoshimi; Zhang, Yi; Horng, Herng Er; Liao, Shu Hsien; Yang, Hong Chang.

    In: IEEE Transactions on Magnetics, Vol. 51, No. 2, 6502504, 01.02.2015.

    Research output: Contribution to journalArticle

    Tanaka, Saburo ; Murata, Hayaki ; Oishi, Tomoya ; Hatsukade, Yoshimi ; Zhang, Yi ; Horng, Herng Er ; Liao, Shu Hsien ; Yang, Hong Chang. / Imaging of Magnetic Nanoparticles Using a Second Harmonic of Magnetization With DC Bias Field. In: IEEE Transactions on Magnetics. 2015 ; Vol. 51, No. 2.
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