Hybrid Nano Plasmonics for Integrated Biosensor

Chii Wann Lin, Jun Haw Lee, Nan Fu Chiu, Szu Yuan Lee, Kou Chen Liu, Feng Yu Tsai, Chia Yu Yen, Chun Nan Lee

Research output: Chapter in Book/Report/Conference proceedingConference contribution


SPR biosensor with OLED and nano-grating for HBV LAMP product detection is reported. Directional emissions by grating-coupler match the resonant condition of SP modes. Concentration changes result in color shift at specific angle. Real time detection of virus load down to 5 copies/25 ul can be achieved in 30 minutes. Surface plasmon Resonant (SPR) biosensor has been used for quantitative measurement of molecular interactions for its advantages of high sensitivity, label-free and real-time detection. In this paper, we report recent efforts on further enhancement of SPR biosensors by the heterogeneous integration of organic electroluminescence light source and nano-grating structure for the feasibility study on the fast and high sensitivity detection of HBV isothermal amplification products, Mg2P207. We demonstrated the surface plasmon coupled through hybrid nano-grating structure has highly directional emissions corresponding to the resonant condition of surface plasmon modes on the Au/air interface and controllable plasmonics band-gap by pitch modulation. SPGCE resulted in color change from yellowish green to orange at a certain viewing angle, when contacting glucose with concentration increasing from 10 to 40%.

Original languageEnglish
Title of host publicationOptical Sensors and Biophotonics
Publication statusPublished - 2009
EventOptical Sensors and Biophotonics - Shanghai, China
Duration: 2009 Nov 22009 Nov 6

Publication series

NameProceedings of SPIE - The International Society for Optical Engineering
ISSN (Print)0277-786X


OtherOptical Sensors and Biophotonics


  • (170.3890) medical optics instrumentation
  • (240.6680) surface plasmons

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Condensed Matter Physics
  • Computer Science Applications
  • Applied Mathematics
  • Electrical and Electronic Engineering


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