FK-506 synthetic studies. 3. An efficient asymmetric synthesis of the C(24)-C(34) fragment of FK-506, FR-900520, and FR-900523

Amos B. Smith; Karl J. Hale; Leif M. Laakso; Kwunmin Chen; Antoni Riéra

doi:10.1016/S0040-4039(01)93398-2

FK-506 synthetic studies. 3. An efficient asymmetric synthesis of the C(24)-C(34) fragment of FK-506, FR-900520, and FR-900523

Amos B. Smith, Karl J. Hale, Leif M. Laakso, Kwunmin Chen, Antoni Riéra

Department of Chemistry

Research output: Contribution to journal › Article

72 Citations (Scopus)

Abstract

An efficient asymmetric synthesis of the C(24)-C(34) fragment of the FK-506 family of immunosuppressants has been achieved.

Original language	English
Pages (from-to)	6963-6966
Number of pages	4
Journal	Tetrahedron Letters
Volume	30
Issue number	50
DOIs	https://doi.org/10.1016/S0040-4039(01)93398-2
Publication status	Published - 1989

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ASJC Scopus subject areas

Biochemistry
Drug Discovery
Organic Chemistry

Cite this

Smith, A. B., Hale, K. J., Laakso, L. M., Chen, K., & Riéra, A. (1989). FK-506 synthetic studies. 3. An efficient asymmetric synthesis of the C(24)-C(34) fragment of FK-506, FR-900520, and FR-900523. Tetrahedron Letters, 30(50), 6963-6966. https://doi.org/10.1016/S0040-4039(01)93398-2

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abstract = "An efficient asymmetric synthesis of the C(24)-C(34) fragment of the FK-506 family of immunosuppressants has been achieved.",

author = "Smith, {Amos B.} and Hale, {Karl J.} and Laakso, {Leif M.} and Kwunmin Chen and Antoni Ri{\'e}ra",

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10.1016/S0040-4039(01)93398-2