FK-506 synthetic studies. 3. An efficient asymmetric synthesis of the C(24)-C(34) fragment of FK-506, FR-900520, and FR-900523

Amos B. Smith, Karl J. Hale, Leif M. Laakso, Kwunmin Chen, Antoni Riéra

Research output: Contribution to journal › Article

72 Citations (Scopus)

Abstract

An efficient asymmetric synthesis of the C(24)-C(34) fragment of the FK-506 family of immunosuppressants has been achieved.

Original languageEnglish
Pages (from-to)6963-6966
Number of pages4
JournalTetrahedron Letters
Volume30
Issue number50
DOIs
Publication statusPublished - 1989

Fingerprint

Tacrolimus
Immunosuppressive Agents
immunomycin
FR 900523

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

Cite this

FK-506 synthetic studies. 3. An efficient asymmetric synthesis of the C(24)-C(34) fragment of FK-506, FR-900520, and FR-900523. / Smith, Amos B.; Hale, Karl J.; Laakso, Leif M.; Chen, Kwunmin; Riéra, Antoni.

In: Tetrahedron Letters, Vol. 30, No. 50, 1989, p. 6963-6966.

Research output: Contribution to journal › Article

Smith, AB, Hale, KJ, Laakso, LM, Chen, K & Riéra, A 1989, 'FK-506 synthetic studies. 3. An efficient asymmetric synthesis of the C(24)-C(34) fragment of FK-506, FR-900520, and FR-900523', Tetrahedron Letters, vol. 30, no. 50, pp. 6963-6966. https://doi.org/10.1016/S0040-4039(01)93398-2
Smith AB, Hale KJ, Laakso LM, Chen K, Riéra A. FK-506 synthetic studies. 3. An efficient asymmetric synthesis of the C(24)-C(34) fragment of FK-506, FR-900520, and FR-900523. Tetrahedron Letters. 1989;30(50):6963-6966. https://doi.org/10.1016/S0040-4039(01)93398-2
Smith, Amos B. ; Hale, Karl J. ; Laakso, Leif M. ; Chen, Kwunmin ; Riéra, Antoni. / FK-506 synthetic studies. 3. An efficient asymmetric synthesis of the C(24)-C(34) fragment of FK-506, FR-900520, and FR-900523. In: Tetrahedron Letters. 1989 ; Vol. 30, No. 50. pp. 6963-6966.
@article{ec9adf8624c34065a3d17c3f08a6498a,
title = "FK-506 synthetic studies. 3. An efficient asymmetric synthesis of the C(24)-C(34) fragment of FK-506, FR-900520, and FR-900523",
abstract = "An efficient asymmetric synthesis of the C(24)-C(34) fragment of the FK-506 family of immunosuppressants has been achieved.",
author = "Smith, {Amos B.} and Hale, {Karl J.} and Laakso, {Leif M.} and Kwunmin Chen and Antoni Ri{\'e}ra",
year = "1989",
doi = "10.1016/S0040-4039(01)93398-2",
language = "English",
volume = "30",
pages = "6963--6966",
journal = "Tetrahedron Letters",
issn = "0040-4039",
publisher = "Elsevier Limited",
number = "50",

}

TY - JOUR

T1 - FK-506 synthetic studies. 3. An efficient asymmetric synthesis of the C(24)-C(34) fragment of FK-506, FR-900520, and FR-900523

AU - Smith, Amos B.

AU - Hale, Karl J.

AU - Laakso, Leif M.

AU - Chen, Kwunmin

AU - Riéra, Antoni

PY - 1989

Y1 - 1989

N2 - An efficient asymmetric synthesis of the C(24)-C(34) fragment of the FK-506 family of immunosuppressants has been achieved.

AB - An efficient asymmetric synthesis of the C(24)-C(34) fragment of the FK-506 family of immunosuppressants has been achieved.

UR - http://www.scopus.com/inward/record.url?scp=0024791572&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0024791572&partnerID=8YFLogxK

U2 - 10.1016/S0040-4039(01)93398-2

DO - 10.1016/S0040-4039(01)93398-2

M3 - Article

AN - SCOPUS:0024791572

VL - 30

SP - 6963

EP - 6966

JO - Tetrahedron Letters

JF - Tetrahedron Letters

SN - 0040-4039

IS - 50

ER -

Access to Document