FK-506 synthetic studies. 3. An efficient asymmetric synthesis of the C(24)-C(34) fragment of FK-506, FR-900520, and FR-900523

Amos B. Smith; Karl J. Hale; Leif M. Laakso; Kwunmin Chen; Antoni Riéra

doi:10.1016/S0040-4039(01)93398-2

FK-506 synthetic studies. 3. An efficient asymmetric synthesis of the C(24)-C(34) fragment of FK-506, FR-900520, and FR-900523

Amos B. Smith, Karl J. Hale, Leif M. Laakso, Kwunmin Chen, Antoni Riéra

Department of Chemistry

Research output: Contribution to journal › Article › peer-review

73 Citations (Scopus)

Abstract

An efficient asymmetric synthesis of the C(24)-C(34) fragment of the FK-506 family of immunosuppressants has been achieved.

Original language	English
Pages (from-to)	6963-6966
Number of pages	4
Journal	Tetrahedron Letters
Volume	30
Issue number	50
DOIs	https://doi.org/10.1016/S0040-4039(01)93398-2
Publication status	Published - 1989

ASJC Scopus subject areas

Biochemistry
Drug Discovery
Organic Chemistry

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title = "FK-506 synthetic studies. 3. An efficient asymmetric synthesis of the C(24)-C(34) fragment of FK-506, FR-900520, and FR-900523",

abstract = "An efficient asymmetric synthesis of the C(24)-C(34) fragment of the FK-506 family of immunosuppressants has been achieved.",

author = "Smith, {Amos B.} and Hale, {Karl J.} and Laakso, {Leif M.} and Kwunmin Chen and Antoni Ri{\'e}ra",

year = "1989",

doi = "10.1016/S0040-4039(01)93398-2",

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T1 - FK-506 synthetic studies. 3. An efficient asymmetric synthesis of the C(24)-C(34) fragment of FK-506, FR-900520, and FR-900523

AU - Smith, Amos B.

AU - Hale, Karl J.

AU - Laakso, Leif M.

AU - Chen, Kwunmin

AU - Riéra, Antoni

PY - 1989

Y1 - 1989

N2 - An efficient asymmetric synthesis of the C(24)-C(34) fragment of the FK-506 family of immunosuppressants has been achieved.

AB - An efficient asymmetric synthesis of the C(24)-C(34) fragment of the FK-506 family of immunosuppressants has been achieved.

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U2 - 10.1016/S0040-4039(01)93398-2

DO - 10.1016/S0040-4039(01)93398-2

M3 - Article

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VL - 30

SP - 6963

EP - 6966

JO - Tetrahedron Letters

JF - Tetrahedron Letters

SN - 0040-4039

IS - 50

ER -