FeCl3 catalyzed regioselective C -alkylation of indolylnitroalkenes with amino group substituted arenes

Manoj R. Zanwar, Veerababurao Kavala, Sachin D. Gawande, Chun Wei Kuo, Wen Chang Huang, Ting Shen Kuo, Hsiu Ni Huang, Chiu Hui He, Ching Fa Yao

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

An efficient FeCl3 catalyzed protocol for the synthesis of amino functionalized indolylnitroalkanes from easily available precursor indolylnitroalkenes and substituted amines has been developed. Regioselective C-alkylation in the presence of free amino substituted arenes occurred. The scope of this methodology shows good functional group tolerance, and further, this protocol was used to prepare indolylquinoline derivatives.

Original languageEnglish
Pages (from-to)1842-1849
Number of pages8
JournalJournal of Organic Chemistry
Volume79
Issue number4
DOIs
Publication statusPublished - 2014 Feb 21

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Alkylation
Functional groups
Amines
Derivatives

ASJC Scopus subject areas

  • Organic Chemistry

Cite this

FeCl3 catalyzed regioselective C -alkylation of indolylnitroalkenes with amino group substituted arenes. / Zanwar, Manoj R.; Kavala, Veerababurao; Gawande, Sachin D.; Kuo, Chun Wei; Huang, Wen Chang; Kuo, Ting Shen; Huang, Hsiu Ni; He, Chiu Hui; Yao, Ching Fa.

In: Journal of Organic Chemistry, Vol. 79, No. 4, 21.02.2014, p. 1842-1849.

Research output: Contribution to journalArticle

Zanwar, MR, Kavala, V, Gawande, SD, Kuo, CW, Huang, WC, Kuo, TS, Huang, HN, He, CH & Yao, CF 2014, 'FeCl3 catalyzed regioselective C -alkylation of indolylnitroalkenes with amino group substituted arenes', Journal of Organic Chemistry, vol. 79, no. 4, pp. 1842-1849. https://doi.org/10.1021/jo4025368
Zanwar, Manoj R. ; Kavala, Veerababurao ; Gawande, Sachin D. ; Kuo, Chun Wei ; Huang, Wen Chang ; Kuo, Ting Shen ; Huang, Hsiu Ni ; He, Chiu Hui ; Yao, Ching Fa. / FeCl3 catalyzed regioselective C -alkylation of indolylnitroalkenes with amino group substituted arenes. In: Journal of Organic Chemistry. 2014 ; Vol. 79, No. 4. pp. 1842-1849.
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AU - Kuo, Chun Wei

AU - Huang, Wen Chang

AU - Kuo, Ting Shen

AU - Huang, Hsiu Ni

AU - He, Chiu Hui

AU - Yao, Ching Fa

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