FeCl3 catalyzed regioselective C -alkylation of indolylnitroalkenes with amino group substituted arenes

Manoj R. Zanwar, Veerababurao Kavala, Sachin D. Gawande, Chun Wei Kuo, Wen Chang Huang, Ting Shen Kuo, Hsiu Ni Huang, Chiu Hui He, Ching Fa Yao

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4 Citations (Scopus)

Abstract

An efficient FeCl3 catalyzed protocol for the synthesis of amino functionalized indolylnitroalkanes from easily available precursor indolylnitroalkenes and substituted amines has been developed. Regioselective C-alkylation in the presence of free amino substituted arenes occurred. The scope of this methodology shows good functional group tolerance, and further, this protocol was used to prepare indolylquinoline derivatives.

Original languageEnglish
Pages (from-to)1842-1849
Number of pages8
JournalJournal of Organic Chemistry
Volume79
Issue number4
DOIs
Publication statusPublished - 2014 Feb 21

ASJC Scopus subject areas

  • Organic Chemistry

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    Zanwar, M. R., Kavala, V., Gawande, S. D., Kuo, C. W., Huang, W. C., Kuo, T. S., Huang, H. N., He, C. H., & Yao, C. F. (2014). FeCl3 catalyzed regioselective C -alkylation of indolylnitroalkenes with amino group substituted arenes. Journal of Organic Chemistry, 79(4), 1842-1849. https://doi.org/10.1021/jo4025368