Abstract
C-Alkylation of 2-hydroxy-1,4-naphthoquinone to various nitroolefins was achieved under catalyst-free employing 'on water' conditions. The mechanism for the formation can be explained on the basis of dual activation of nitroalkene and 2-hydroxy-1,4-naphthoquinones via hydrogen bonding. Simple reaction conditions, high yields of the products, and environmentally benign medium are attractive features of this method.
Original language | English |
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Pages (from-to) | 5116-5119 |
Number of pages | 4 |
Journal | Tetrahedron Letters |
Volume | 50 |
Issue number | 36 |
DOIs | |
Publication status | Published - 2009 Sept 9 |
ASJC Scopus subject areas
- Biochemistry
- Drug Discovery
- Organic Chemistry
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CCDC 720909: Experimental Crystal Structure Determination
Barange, D. K. (Creator), Kavala, V. (Creator), Raju, B. R. (Creator), Kuo, C. (Creator), Tseng, C. (Creator), Tu, Y. (Creator) & Yao, C. (Creator), Unknown Publisher, 2010
DOI: 10.5517/ccs6548, http://www.ccdc.cam.ac.uk/services/structure_request?id=doi:10.5517/ccs6548&sid=DataCite
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