Excellent diastereoselective allylation of camphor derived glyoxylic oxime ethers mediated by a Lewis acid

Neelesh A. Kulkarni, Kwunmin Chen

Research output: Contribution to journalArticle

16 Citations (Scopus)

Abstract

The nucleophilic allylation of camphor derived glyoxylic oxime ethers was carried out using allyltributyltin in the presence of Sn(OTf)2 affording the corresponding homoallylic amines in high chemical yields (up to 94%) and excellent stereoselectivities (up to >99%).

Original languageEnglish
Pages (from-to)611-613
Number of pages3
JournalTetrahedron Letters
Volume47
Issue number4
DOIs
Publication statusPublished - 2006 Jan 23

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Allylation
Camphor
Stereoselectivity
Lewis Acids
Amines
glyoxylic oxime ether

ASJC Scopus subject areas

  • Biochemistry
  • Organic Chemistry
  • Drug Discovery

Cite this

Excellent diastereoselective allylation of camphor derived glyoxylic oxime ethers mediated by a Lewis acid. / Kulkarni, Neelesh A.; Chen, Kwunmin.

In: Tetrahedron Letters, Vol. 47, No. 4, 23.01.2006, p. 611-613.

Research output: Contribution to journalArticle

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