Evaluation of an affinity-amplified immunoassay of graphene oxide using surface plasmon resonance biosensors

Nan Fu Chiu*, Teng Yi Huang, Chun Chuan Kuo

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingConference contribution

2 Citations (Scopus)


We describe a fundamental study on the plasmonic properties and advanced biosensing mechanisms of functionalized graphene. We discuss a specific design using modified carboxyl groups, which can modulate surface plasmon (SP) coupling and provide an advantage for their binding to the sensing layer with high-performance affinity in an immunological reaction. The functionalized graphene-based surface plasmon resonance (SPR) biosensors have three advantages: high performance, high sensitivity, and excellent molecular kinetic response. In the future, functionalized graphene sheets will make a unique contribution to photonic and SPR diagnosis devices. We wish to highlight the essential characteristics of functionalized graphene-based SPR biosensors to assist researchers in developing and advancing suitable biosensors for unique applications.

Original languageEnglish
Title of host publicationOptical Sensors 2015
EditorsFrancesco Baldini, Robert A. Lieberman, Jiri Homola
ISBN (Electronic)9781628416275
Publication statusPublished - 2015
EventOptical Sensors 2015 - Prague, Czech Republic
Duration: 2015 Apr 132015 Apr 16

Publication series

NameProceedings of SPIE - The International Society for Optical Engineering
ISSN (Print)0277-786X
ISSN (Electronic)1996-756X


OtherOptical Sensors 2015
Country/TerritoryCzech Republic


  • Biosensor
  • Graphene oxide (GO)
  • Surface plasmon resonance (SPR)

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Condensed Matter Physics
  • Computer Science Applications
  • Applied Mathematics
  • Electrical and Electronic Engineering


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