Enantioselective synthesis of coumarin derivatives catalyzed by primary amines

Yen Te Lee, Utpal Das, Yi Ru Chen, Chia Jui Lee, Chi Han Chen, Mei Chun Yang, Wenwei Lin

Research output: Contribution to journalArticle

17 Citations (Scopus)

Abstract

Cinchona alkaloid-derived primary amines were used as organocatalysts for the preparation of enantioenriched coumarin derivatives. A series of optically active coumarin derivatives was obtained in good yields with excellent enantioselectivities (up to 98% ee).

Original languageEnglish
Pages (from-to)3154-3160
Number of pages7
JournalAdvanced Synthesis and Catalysis
Volume355
Issue number16
DOIs
Publication statusPublished - 2013 Nov 11

Keywords

  • asymmetric catalysis
  • coumarin derivatives
  • Michael addition
  • organocatalysis
  • primary amines

ASJC Scopus subject areas

  • Catalysis
  • Organic Chemistry

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