Enantioselective synthesis of coumarin derivatives catalyzed by primary amines

Yen Te Lee, Utpal Das, Yi Ru Chen, Chia Jui Lee, Chi Han Chen, Mei Chun Yang, Wenwei Lin

Research output: Contribution to journal › Article

14 Citations (Scopus)

Abstract

Cinchona alkaloid-derived primary amines were used as organocatalysts for the preparation of enantioenriched coumarin derivatives. A series of optically active coumarin derivatives was obtained in good yields with excellent enantioselectivities (up to 98% ee).

Original languageEnglish
Pages (from-to)3154-3160
Number of pages7
JournalAdvanced Synthesis and Catalysis
Volume355
Issue number16
DOIs
Publication statusPublished - 2013 Nov 11

Fingerprint

Coumarins
Amines
Cinchona Alkaloids
Derivatives
Enantioselectivity

Keywords

  • asymmetric catalysis
  • coumarin derivatives
  • Michael addition
  • organocatalysis
  • primary amines

ASJC Scopus subject areas

  • Catalysis
  • Organic Chemistry

Cite this

Enantioselective synthesis of coumarin derivatives catalyzed by primary amines. / Lee, Yen Te; Das, Utpal; Chen, Yi Ru; Lee, Chia Jui; Chen, Chi Han; Yang, Mei Chun; Lin, Wenwei.

In: Advanced Synthesis and Catalysis, Vol. 355, No. 16, 11.11.2013, p. 3154-3160.

Research output: Contribution to journal › Article

Lee, YT, Das, U, Chen, YR, Lee, CJ, Chen, CH, Yang, MC & Lin, W 2013, 'Enantioselective synthesis of coumarin derivatives catalyzed by primary amines', Advanced Synthesis and Catalysis, vol. 355, no. 16, pp. 3154-3160. https://doi.org/10.1002/adsc.201300450
Lee YT, Das U, Chen YR, Lee CJ, Chen CH, Yang MC et al. Enantioselective synthesis of coumarin derivatives catalyzed by primary amines. Advanced Synthesis and Catalysis. 2013 Nov 11;355(16):3154-3160. https://doi.org/10.1002/adsc.201300450
Lee, Yen Te ; Das, Utpal ; Chen, Yi Ru ; Lee, Chia Jui ; Chen, Chi Han ; Yang, Mei Chun ; Lin, Wenwei. / Enantioselective synthesis of coumarin derivatives catalyzed by primary amines. In: Advanced Synthesis and Catalysis. 2013 ; Vol. 355, No. 16. pp. 3154-3160.
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