Enantioselective synthesis of coumarin derivatives catalyzed by primary amines

Yen Te Lee, Utpal Das, Yi Ru Chen, Chia Jui Lee, Chi Han Chen, Mei Chun Yang, Wenwei Lin

Research output: Contribution to journalArticle

14 Citations (Scopus)

Abstract

Cinchona alkaloid-derived primary amines were used as organocatalysts for the preparation of enantioenriched coumarin derivatives. A series of optically active coumarin derivatives was obtained in good yields with excellent enantioselectivities (up to 98% ee).

Original languageEnglish
Pages (from-to)3154-3160
Number of pages7
JournalAdvanced Synthesis and Catalysis
Volume355
Issue number16
DOIs
Publication statusPublished - 2013 Nov 11

Fingerprint

Coumarins
Amines
Cinchona Alkaloids
Derivatives
Enantioselectivity

Keywords

  • asymmetric catalysis
  • coumarin derivatives
  • Michael addition
  • organocatalysis
  • primary amines

ASJC Scopus subject areas

  • Catalysis
  • Organic Chemistry

Cite this

Enantioselective synthesis of coumarin derivatives catalyzed by primary amines. / Lee, Yen Te; Das, Utpal; Chen, Yi Ru; Lee, Chia Jui; Chen, Chi Han; Yang, Mei Chun; Lin, Wenwei.

In: Advanced Synthesis and Catalysis, Vol. 355, No. 16, 11.11.2013, p. 3154-3160.

Research output: Contribution to journalArticle

Lee, Yen Te ; Das, Utpal ; Chen, Yi Ru ; Lee, Chia Jui ; Chen, Chi Han ; Yang, Mei Chun ; Lin, Wenwei. / Enantioselective synthesis of coumarin derivatives catalyzed by primary amines. In: Advanced Synthesis and Catalysis. 2013 ; Vol. 355, No. 16. pp. 3154-3160.
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