Enantioselective synthesis of coumarin derivatives catalyzed by primary amines

Yen Te Lee; Utpal Das; Yi Ru Chen; Chia Jui Lee; Chi Han Chen; Mei Chun Yang; Wenwei Lin

doi:10.1002/adsc.201300450

Enantioselective synthesis of coumarin derivatives catalyzed by primary amines

Yen Te Lee, Utpal Das, Yi Ru Chen, Chia Jui Lee, Chi Han Chen, Mei Chun Yang, Wenwei Lin

Department of Chemistry

Research output: Contribution to journal › Article › peer-review

21 Citations (Scopus)

Abstract

Cinchona alkaloid-derived primary amines were used as organocatalysts for the preparation of enantioenriched coumarin derivatives. A series of optically active coumarin derivatives was obtained in good yields with excellent enantioselectivities (up to 98% ee).

Original language	English
Pages (from-to)	3154-3160
Number of pages	7
Journal	Advanced Synthesis and Catalysis
Volume	355
Issue number	16
DOIs	https://doi.org/10.1002/adsc.201300450
Publication status	Published - 2013 Nov 11

Keywords

asymmetric catalysis
coumarin derivatives
Michael addition
organocatalysis
primary amines

ASJC Scopus subject areas

Catalysis
Organic Chemistry

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abstract = "Cinchona alkaloid-derived primary amines were used as organocatalysts for the preparation of enantioenriched coumarin derivatives. A series of optically active coumarin derivatives was obtained in good yields with excellent enantioselectivities (up to 98% ee).",

keywords = "asymmetric catalysis, coumarin derivatives, Michael addition, organocatalysis, primary amines",

author = "Lee, {Yen Te} and Utpal Das and Chen, {Yi Ru} and Lee, {Chia Jui} and Chen, {Chi Han} and Yang, {Mei Chun} and Wenwei Lin",

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AU - Das, Utpal

AU - Chen, Yi Ru

AU - Lee, Chia Jui

AU - Chen, Chi Han

AU - Yang, Mei Chun

AU - Lin, Wenwei

PY - 2013/11/11

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KW - coumarin derivatives

KW - Michael addition

KW - organocatalysis

KW - primary amines

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