Enantioselective Aziridination of Alkenes with N-Aminophthalimide in the Presence of Lead Tetraacetate-Mediated Chiral Ligand

Kung Shou Yang, Kwunmin Chen

Research output: Contribution to journalArticle

33 Citations (Scopus)


matrix presented Reaction of various N-enoyl oxazolidinones 5a-f with N-aminophthalimide and lead tetraacetate in the presence of camphor-derived chiral ligands provides the desired N-phthalimidoaziridines 6a-f in good to high enantiomeric excess (67-95% ee) at 0°C within 15 min. The absolute stereochemistry of the corresponding aziridine derivatives was established by chemical correlations.

Original languageEnglish
Pages (from-to)1107-1109
Number of pages3
JournalOrganic Letters
Issue number7
Publication statusPublished - 2002 Apr 4


ASJC Scopus subject areas

  • Biochemistry
  • Physical and Theoretical Chemistry
  • Organic Chemistry

Cite this