Enantioselective Aziridination of Alkenes with N-Aminophthalimide in the Presence of Lead Tetraacetate-Mediated Chiral Ligand

Kung Shou Yang, Kwunmin Chen

Research output: Contribution to journalArticle

33 Citations (Scopus)

Abstract

matrix presented Reaction of various N-enoyl oxazolidinones 5a-f with N-aminophthalimide and lead tetraacetate in the presence of camphor-derived chiral ligands provides the desired N-phthalimidoaziridines 6a-f in good to high enantiomeric excess (67-95% ee) at 0°C within 15 min. The absolute stereochemistry of the corresponding aziridine derivatives was established by chemical correlations.

Original languageEnglish
Pages (from-to)1107-1109
Number of pages3
JournalOrganic Letters
Volume4
Issue number7
DOIs
Publication statusPublished - 2002 Apr 4

Fingerprint

Oxazolidinones
Camphor
camphor
Stereochemistry
stereochemistry
Alkenes
alkenes
Ligands
Derivatives
ligands
matrices
N-aminophthalimide
aziridine
lead tetraacetate

ASJC Scopus subject areas

  • Biochemistry
  • Physical and Theoretical Chemistry
  • Organic Chemistry

Cite this

Enantioselective Aziridination of Alkenes with N-Aminophthalimide in the Presence of Lead Tetraacetate-Mediated Chiral Ligand. / Yang, Kung Shou; Chen, Kwunmin.

In: Organic Letters, Vol. 4, No. 7, 04.04.2002, p. 1107-1109.

Research output: Contribution to journalArticle

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