Efficient architecture for spike sorting in reconfigurable hardware

Wen Jyi Hwang*, Wei Hao Lee, Shiow Jyu Lin, Sheng Ying Lai

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

14 Citations (Scopus)


This paper presents a novel hardware architecture for fast spike sorting. The architecture is able to perform both the feature extraction and clustering in hardware. The generalized Hebbian algorithm (GHA) and fuzzy C-means (FCM) algorithm are used for feature extraction and clustering, respectively. The employment of GHA allows efficient computation of principal components for subsequent clustering operations. The FCM is able to achieve near optimal clustering for spike sorting. Its performance is insensitive to the selection of initial cluster centers. The hardware implementations of GHA and FCM feature low area costs and high throughput. In the GHA architecture, the computation of different weight vectors share the same circuit for lowering the area costs. Moreover, in the FCM hardware implementation, the usual iterative operations for updating the membership matrix and cluster centroid are merged into one single updating process to evade the large storage requirement. To show the effectiveness of the circuit, the proposed architecture is physically implemented by field programmable gate array (FPGA). It is embedded in a System-on-Chip (SOC) platform for performance measurement. Experimental results show that the proposed architecture is an efficient spike sorting design for attaining high classification correct rate and high speed computation.

Original languageEnglish
Pages (from-to)14860-14887
Number of pages28
JournalSensors (Switzerland)
Issue number11
Publication statusPublished - 2013 Nov 1


  • FPGA
  • Fuzzy C-means
  • Generalized Hebbian algorithm
  • Reconfigurable computing
  • Spike sorting
  • System-on-chip

ASJC Scopus subject areas

  • Analytical Chemistry
  • Biochemistry
  • Atomic and Molecular Physics, and Optics
  • Instrumentation
  • Electrical and Electronic Engineering


Dive into the research topics of 'Efficient architecture for spike sorting in reconfigurable hardware'. Together they form a unique fingerprint.

Cite this