Effects of a 7-day eccentric training period on muscle damage and inflammation

T. C. Chen, S. S. Hsieh

Research output: Contribution to journalArticle

84 Citations (Scopus)

Abstract

Purpose: This study examined the effects of a 7-d repeated maximal isokinetic eccentric training period on the indicators of muscle damage and inflammatory response. Methods: Twenty-two college-age males were randomly assigned to eccentric training (ET) (N=12) and control groups (CON) (N=10). The initial exercise was 30 repetitions of maximal voluntary isokinetic eccentric contraction (ECC1) on nondominant elbow flexors with Cybex 6000 at 60°·s-1 angular velocity. The ET group performed the same exercise for the following 6 consecutive days (referred to as ECC2 to ECC7) after ECC1. Upper ann circumference (CIR), range of motion (ROM), and maximal isometric force (MIF) were measured before, immediately after, and every 24 h for 7 consecutive days after ECC1. Plasma creatine kinase (CK), lactate dehydrogenase (LDH), glutamic oxaloacetate transaminase (GOT), leukocyte counts, and serum interleukin-1β and -6 (IL-1β, IL-6) levels were assessed before; at 2 h; and at 1, 3, 4, 6, and 7 d after ECC1. Muscle soreness was measured before and for 7 consecutive days after ECC1. Results: The ECC1 produced significant changes in most of the measures for both groups (P<0.05), with the exception of leukocyte counts (P>0.05). No indicators of increased damage (P>0.05) were found from ECC2 to ECC7 for the ET group. Conclusion: Continuous intensive isokinetic eccentric training performed with damaged muscles did not exacerbate muscle damage and inflammation after ECC1. In addition, a muscular "adaptation effect" may occur as early as 24 h after ECC1, as shown by the ET group's performance for 6 consecutive days after ECC1.

Original languageEnglish
Pages (from-to)1732-1738
Number of pages7
JournalMedicine and Science in Sports and Exercise
Volume33
Issue number10
DOIs
Publication statusPublished - 2001 Jan 1

Fingerprint

Inflammation
Interleukin-1
Muscles
Interleukin-6
Oxaloacetic Acid
Myalgia
Creatine Kinase
Elbow
Articular Range of Motion
Transaminases
Leukocyte Count
L-Lactate Dehydrogenase
Control Groups
Serum

Keywords

  • Adaptation effect
  • Creatine kinase
  • Interleukin-1β
  • Total work

ASJC Scopus subject areas

  • Orthopedics and Sports Medicine
  • Physical Therapy, Sports Therapy and Rehabilitation

Cite this

Effects of a 7-day eccentric training period on muscle damage and inflammation. / Chen, T. C.; Hsieh, S. S.

In: Medicine and Science in Sports and Exercise, Vol. 33, No. 10, 01.01.2001, p. 1732-1738.

Research output: Contribution to journalArticle

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