Effect of passive repetitive isokinetic training on cytokines and hormonal changes

Shu Lin Lee, Kenny Wen Chyuan Chen, Szu Tah Chen, Po Ju Chu, Chuan Show Chen, Mei Chich Hsu, Tzyy-Yuang Shiang, Mao Kuan Su, Mu San Chang, Ying Ling Chang, Shyi Wu Wang

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

It is well known that muscle strength and power are important factors in exercise. Plyometrics is designed to gain muscle strength and power in a shock method. The passive repetitive isokinetic (PRI) machine is developed for plyometrics. The present study aims to understand the effect of ten-week PRI training in different intensities on human plasma concentration cytokines as well as hormonal changes. Thirty young male subjects were enrolled into the ten-week PRI training program and were divided randomly into traditional, low-and high-intensity PRI training groups. Blood samples were obtained before, during, after and 1-, 2-, 3-, 5-and 7-day (D) post-training. The plasma concentrations of cytokines and hormones were measured by an enzyme-linked immunosorbent assay (ELISA). Elevated plasma IL-2 was found in the subjects in all the training programs. Significant increases of proinflammatory cytokines IL-1β and TNF-α were observed at post 7 D in the high-intensity PRI training (29.5 ± 4.4 and 515.8 ± 127.1 pg/ml, respectively). No significance in differences in the plasma concentration of IL-6 was observed in the traditional and low-intensity PRI training. Significant elevation of IL-6 was found at post 5 D in high-intensity PRI training. Higher plasma IL-6 concentration was observed at post 3 and 5 D in high-intensity PRI training compared to low-intensity PRI training (P < 0.05). Significant elevation of plasma IL-15 during (week 6) and after (post 0 D) was observed in lowintensity PRI training. Also, there were differences between low-intensity PRI training and traditional training at post 0, 2, 3, and 5 D. The plasma concentration of cortisol was decreased to the lowest value (118.0 ± 17.3 ng/ml) at post 0 D in traditional training, then returned to the baseline (220.5 ± 19.1 ng/ml). In the high-intensity PRI training, but not in the low-intensity PRI training, the cortisol level dropped from 224.9 ± 25.8 ng/ml at post 0 D down to the 123.2 ± 22.6 ng/ml at post 1 D. Significant differences were found at post 1 and 5 D between low-and high-intensity PRI training, and post 0, 1, 2, and 3 D between traditional and high-intensity PRI training. Significant increased testosterone was found post 0, 1, 2, and 3 D in traditional training. Higher plasma testosterone was observed during and the recovery period in low-intensity, but not in high-intensity, PRI training. In conclusion, high-intensity PRI training could induce the proinflammatory cytokines, i.e. IL-1β and TNF-α, and decrease plasma cortisol in the recovery period.

Original languageEnglish
Pages (from-to)55-66
Number of pages12
JournalChinese Journal of Physiology
Volume54
Issue number1
DOIs
Publication statusPublished - 2011 Jan 1

Fingerprint

Cytokines
Hydrocortisone
Interleukin-6
Muscle Strength
Interleukin-1
Testosterone
Education
Interleukin-15
Interleukin-2
Shock
Enzyme-Linked Immunosorbent Assay
Hormones

Keywords

  • Cytokine
  • Hormone
  • Human
  • PRI
  • Passive repetitive isokinetic training

ASJC Scopus subject areas

  • Physiology
  • Physiology (medical)

Cite this

Lee, S. L., Chen, K. W. C., Chen, S. T., Chu, P. J., Chen, C. S., Hsu, M. C., ... Wang, S. W. (2011). Effect of passive repetitive isokinetic training on cytokines and hormonal changes. Chinese Journal of Physiology, 54(1), 55-66. https://doi.org/10.4077/CJP.2011.AMM086

Effect of passive repetitive isokinetic training on cytokines and hormonal changes. / Lee, Shu Lin; Chen, Kenny Wen Chyuan; Chen, Szu Tah; Chu, Po Ju; Chen, Chuan Show; Hsu, Mei Chich; Shiang, Tzyy-Yuang; Su, Mao Kuan; Chang, Mu San; Chang, Ying Ling; Wang, Shyi Wu.

In: Chinese Journal of Physiology, Vol. 54, No. 1, 01.01.2011, p. 55-66.

Research output: Contribution to journalArticle

Lee, SL, Chen, KWC, Chen, ST, Chu, PJ, Chen, CS, Hsu, MC, Shiang, T-Y, Su, MK, Chang, MS, Chang, YL & Wang, SW 2011, 'Effect of passive repetitive isokinetic training on cytokines and hormonal changes', Chinese Journal of Physiology, vol. 54, no. 1, pp. 55-66. https://doi.org/10.4077/CJP.2011.AMM086
Lee, Shu Lin ; Chen, Kenny Wen Chyuan ; Chen, Szu Tah ; Chu, Po Ju ; Chen, Chuan Show ; Hsu, Mei Chich ; Shiang, Tzyy-Yuang ; Su, Mao Kuan ; Chang, Mu San ; Chang, Ying Ling ; Wang, Shyi Wu. / Effect of passive repetitive isokinetic training on cytokines and hormonal changes. In: Chinese Journal of Physiology. 2011 ; Vol. 54, No. 1. pp. 55-66.
@article{508d18794c374018b23e7b2e513e81d2,
title = "Effect of passive repetitive isokinetic training on cytokines and hormonal changes",
abstract = "It is well known that muscle strength and power are important factors in exercise. Plyometrics is designed to gain muscle strength and power in a shock method. The passive repetitive isokinetic (PRI) machine is developed for plyometrics. The present study aims to understand the effect of ten-week PRI training in different intensities on human plasma concentration cytokines as well as hormonal changes. Thirty young male subjects were enrolled into the ten-week PRI training program and were divided randomly into traditional, low-and high-intensity PRI training groups. Blood samples were obtained before, during, after and 1-, 2-, 3-, 5-and 7-day (D) post-training. The plasma concentrations of cytokines and hormones were measured by an enzyme-linked immunosorbent assay (ELISA). Elevated plasma IL-2 was found in the subjects in all the training programs. Significant increases of proinflammatory cytokines IL-1β and TNF-α were observed at post 7 D in the high-intensity PRI training (29.5 ± 4.4 and 515.8 ± 127.1 pg/ml, respectively). No significance in differences in the plasma concentration of IL-6 was observed in the traditional and low-intensity PRI training. Significant elevation of IL-6 was found at post 5 D in high-intensity PRI training. Higher plasma IL-6 concentration was observed at post 3 and 5 D in high-intensity PRI training compared to low-intensity PRI training (P < 0.05). Significant elevation of plasma IL-15 during (week 6) and after (post 0 D) was observed in lowintensity PRI training. Also, there were differences between low-intensity PRI training and traditional training at post 0, 2, 3, and 5 D. The plasma concentration of cortisol was decreased to the lowest value (118.0 ± 17.3 ng/ml) at post 0 D in traditional training, then returned to the baseline (220.5 ± 19.1 ng/ml). In the high-intensity PRI training, but not in the low-intensity PRI training, the cortisol level dropped from 224.9 ± 25.8 ng/ml at post 0 D down to the 123.2 ± 22.6 ng/ml at post 1 D. Significant differences were found at post 1 and 5 D between low-and high-intensity PRI training, and post 0, 1, 2, and 3 D between traditional and high-intensity PRI training. Significant increased testosterone was found post 0, 1, 2, and 3 D in traditional training. Higher plasma testosterone was observed during and the recovery period in low-intensity, but not in high-intensity, PRI training. In conclusion, high-intensity PRI training could induce the proinflammatory cytokines, i.e. IL-1β and TNF-α, and decrease plasma cortisol in the recovery period.",
keywords = "Cytokine, Hormone, Human, PRI, Passive repetitive isokinetic training",
author = "Lee, {Shu Lin} and Chen, {Kenny Wen Chyuan} and Chen, {Szu Tah} and Chu, {Po Ju} and Chen, {Chuan Show} and Hsu, {Mei Chich} and Tzyy-Yuang Shiang and Su, {Mao Kuan} and Chang, {Mu San} and Chang, {Ying Ling} and Wang, {Shyi Wu}",
year = "2011",
month = "1",
day = "1",
doi = "10.4077/CJP.2011.AMM086",
language = "English",
volume = "54",
pages = "55--66",
journal = "Chinese Journal of Physiology",
issn = "0304-4920",
publisher = "Chinese Physiological Society",
number = "1",

}

TY - JOUR

T1 - Effect of passive repetitive isokinetic training on cytokines and hormonal changes

AU - Lee, Shu Lin

AU - Chen, Kenny Wen Chyuan

AU - Chen, Szu Tah

AU - Chu, Po Ju

AU - Chen, Chuan Show

AU - Hsu, Mei Chich

AU - Shiang, Tzyy-Yuang

AU - Su, Mao Kuan

AU - Chang, Mu San

AU - Chang, Ying Ling

AU - Wang, Shyi Wu

PY - 2011/1/1

Y1 - 2011/1/1

N2 - It is well known that muscle strength and power are important factors in exercise. Plyometrics is designed to gain muscle strength and power in a shock method. The passive repetitive isokinetic (PRI) machine is developed for plyometrics. The present study aims to understand the effect of ten-week PRI training in different intensities on human plasma concentration cytokines as well as hormonal changes. Thirty young male subjects were enrolled into the ten-week PRI training program and were divided randomly into traditional, low-and high-intensity PRI training groups. Blood samples were obtained before, during, after and 1-, 2-, 3-, 5-and 7-day (D) post-training. The plasma concentrations of cytokines and hormones were measured by an enzyme-linked immunosorbent assay (ELISA). Elevated plasma IL-2 was found in the subjects in all the training programs. Significant increases of proinflammatory cytokines IL-1β and TNF-α were observed at post 7 D in the high-intensity PRI training (29.5 ± 4.4 and 515.8 ± 127.1 pg/ml, respectively). No significance in differences in the plasma concentration of IL-6 was observed in the traditional and low-intensity PRI training. Significant elevation of IL-6 was found at post 5 D in high-intensity PRI training. Higher plasma IL-6 concentration was observed at post 3 and 5 D in high-intensity PRI training compared to low-intensity PRI training (P < 0.05). Significant elevation of plasma IL-15 during (week 6) and after (post 0 D) was observed in lowintensity PRI training. Also, there were differences between low-intensity PRI training and traditional training at post 0, 2, 3, and 5 D. The plasma concentration of cortisol was decreased to the lowest value (118.0 ± 17.3 ng/ml) at post 0 D in traditional training, then returned to the baseline (220.5 ± 19.1 ng/ml). In the high-intensity PRI training, but not in the low-intensity PRI training, the cortisol level dropped from 224.9 ± 25.8 ng/ml at post 0 D down to the 123.2 ± 22.6 ng/ml at post 1 D. Significant differences were found at post 1 and 5 D between low-and high-intensity PRI training, and post 0, 1, 2, and 3 D between traditional and high-intensity PRI training. Significant increased testosterone was found post 0, 1, 2, and 3 D in traditional training. Higher plasma testosterone was observed during and the recovery period in low-intensity, but not in high-intensity, PRI training. In conclusion, high-intensity PRI training could induce the proinflammatory cytokines, i.e. IL-1β and TNF-α, and decrease plasma cortisol in the recovery period.

AB - It is well known that muscle strength and power are important factors in exercise. Plyometrics is designed to gain muscle strength and power in a shock method. The passive repetitive isokinetic (PRI) machine is developed for plyometrics. The present study aims to understand the effect of ten-week PRI training in different intensities on human plasma concentration cytokines as well as hormonal changes. Thirty young male subjects were enrolled into the ten-week PRI training program and were divided randomly into traditional, low-and high-intensity PRI training groups. Blood samples were obtained before, during, after and 1-, 2-, 3-, 5-and 7-day (D) post-training. The plasma concentrations of cytokines and hormones were measured by an enzyme-linked immunosorbent assay (ELISA). Elevated plasma IL-2 was found in the subjects in all the training programs. Significant increases of proinflammatory cytokines IL-1β and TNF-α were observed at post 7 D in the high-intensity PRI training (29.5 ± 4.4 and 515.8 ± 127.1 pg/ml, respectively). No significance in differences in the plasma concentration of IL-6 was observed in the traditional and low-intensity PRI training. Significant elevation of IL-6 was found at post 5 D in high-intensity PRI training. Higher plasma IL-6 concentration was observed at post 3 and 5 D in high-intensity PRI training compared to low-intensity PRI training (P < 0.05). Significant elevation of plasma IL-15 during (week 6) and after (post 0 D) was observed in lowintensity PRI training. Also, there were differences between low-intensity PRI training and traditional training at post 0, 2, 3, and 5 D. The plasma concentration of cortisol was decreased to the lowest value (118.0 ± 17.3 ng/ml) at post 0 D in traditional training, then returned to the baseline (220.5 ± 19.1 ng/ml). In the high-intensity PRI training, but not in the low-intensity PRI training, the cortisol level dropped from 224.9 ± 25.8 ng/ml at post 0 D down to the 123.2 ± 22.6 ng/ml at post 1 D. Significant differences were found at post 1 and 5 D between low-and high-intensity PRI training, and post 0, 1, 2, and 3 D between traditional and high-intensity PRI training. Significant increased testosterone was found post 0, 1, 2, and 3 D in traditional training. Higher plasma testosterone was observed during and the recovery period in low-intensity, but not in high-intensity, PRI training. In conclusion, high-intensity PRI training could induce the proinflammatory cytokines, i.e. IL-1β and TNF-α, and decrease plasma cortisol in the recovery period.

KW - Cytokine

KW - Hormone

KW - Human

KW - PRI

KW - Passive repetitive isokinetic training

UR - http://www.scopus.com/inward/record.url?scp=79955519792&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=79955519792&partnerID=8YFLogxK

U2 - 10.4077/CJP.2011.AMM086

DO - 10.4077/CJP.2011.AMM086

M3 - Article

C2 - 21786539

AN - SCOPUS:79955519792

VL - 54

SP - 55

EP - 66

JO - Chinese Journal of Physiology

JF - Chinese Journal of Physiology

SN - 0304-4920

IS - 1

ER -