Driven translocation dynamics of polynucleotides through a nanopore: Off-lattice Monte-Carlo simulations

C. M. Chen

doi:10.1016/j.physa.2004.11.026

Driven translocation dynamics of polynucleotides through a nanopore: Off-lattice Monte-Carlo simulations

C. M. Chen^*

^*Corresponding author for this work

Department of Physics

Research output: Contribution to journal › Article › peer-review

21 Citations (Scopus)

Abstract

The driven translocation dynamics of a polynucleotide chain through a nanopore is studied using off-lattice Monte-Carlo simulations, which plays an important role in the nanopore sequencing of polynucleotides. We report a detailed study on the dependence of translocation dynamics on the chain length and the local geometry near the nanopore. In particular, we find that the length dependence of the infection time of the chain could exhibit very different behaviors for different geometries.

Original language	English
Pages (from-to)	95-107
Number of pages	13
Journal	Physica A: Statistical Mechanics and its Applications
Volume	350
Issue number	1
DOIs	https://doi.org/10.1016/j.physa.2004.11.026
Publication status	Published - 2005 May 1

ASJC Scopus subject areas

Statistics and Probability
Condensed Matter Physics

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10.1016/j.physa.2004.11.026

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title = "Driven translocation dynamics of polynucleotides through a nanopore: Off-lattice Monte-Carlo simulations",

abstract = "The driven translocation dynamics of a polynucleotide chain through a nanopore is studied using off-lattice Monte-Carlo simulations, which plays an important role in the nanopore sequencing of polynucleotides. We report a detailed study on the dependence of translocation dynamics on the chain length and the local geometry near the nanopore. In particular, we find that the length dependence of the infection time of the chain could exhibit very different behaviors for different geometries.",

author = "Chen, \{C. M.\}",

note = "Funding Information: The author acknowledges the support from NSC of Taiwan under Grant No. 92-2112-M-003-005 and from National Taiwan Normal University under Grant No. ORD92-3.",

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Y1 - 2005/5/1

N2 - The driven translocation dynamics of a polynucleotide chain through a nanopore is studied using off-lattice Monte-Carlo simulations, which plays an important role in the nanopore sequencing of polynucleotides. We report a detailed study on the dependence of translocation dynamics on the chain length and the local geometry near the nanopore. In particular, we find that the length dependence of the infection time of the chain could exhibit very different behaviors for different geometries.

AB - The driven translocation dynamics of a polynucleotide chain through a nanopore is studied using off-lattice Monte-Carlo simulations, which plays an important role in the nanopore sequencing of polynucleotides. We report a detailed study on the dependence of translocation dynamics on the chain length and the local geometry near the nanopore. In particular, we find that the length dependence of the infection time of the chain could exhibit very different behaviors for different geometries.

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Driven translocation dynamics of polynucleotides through a nanopore: Off-lattice Monte-Carlo simulations

Abstract

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