Driven translocation dynamics of polynucleotides through a nanopore: Off-lattice Monte-Carlo simulations

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21 Citations (Scopus)

Abstract

The driven translocation dynamics of a polynucleotide chain through a nanopore is studied using off-lattice Monte-Carlo simulations, which plays an important role in the nanopore sequencing of polynucleotides. We report a detailed study on the dependence of translocation dynamics on the chain length and the local geometry near the nanopore. In particular, we find that the length dependence of the infection time of the chain could exhibit very different behaviors for different geometries.

Original languageEnglish
Pages (from-to)95-107
Number of pages13
JournalPhysica A: Statistical Mechanics and its Applications
Volume350
Issue number1
DOIs
Publication statusPublished - 2005 May 1

ASJC Scopus subject areas

  • Statistics and Probability
  • Condensed Matter Physics

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