Diversity-oriented synthesis of chromenopyrrolidines from azomethine ylides and 2-hydroxybenzylidene indandiones via base-controlled regiodivergent (3+2) cycloaddition

Jhen Kuei Yu, Han Wei Chien, Yi Jung Lin, Praneeth Karanam, Yu Heng Chen, Wenwei Lin

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

An organobase-directed, regiodivergent 1,3-dipolar cycloaddition of azomethine ylides and 2-hydoxybenzylidene indandiones is reported. The scarcely explored reversal of the nucleophilic site in azomethine ylides has been exploited for their regiodivergent (3+2) cycloaddition, which subsequently resulted in two different cascade processes to generate functionally distinct chromenopyrrolidines in a diversity oriented manner.

Original languageEnglish
Pages (from-to)9921-9924
Number of pages4
JournalChemical Communications
Volume54
Issue number71
DOIs
Publication statusPublished - 2018 Jan 1

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Cycloaddition
Cycloaddition Reaction
azomethine

ASJC Scopus subject areas

  • Catalysis
  • Electronic, Optical and Magnetic Materials
  • Ceramics and Composites
  • Chemistry(all)
  • Surfaces, Coatings and Films
  • Metals and Alloys
  • Materials Chemistry

Cite this

Diversity-oriented synthesis of chromenopyrrolidines from azomethine ylides and 2-hydroxybenzylidene indandiones via base-controlled regiodivergent (3+2) cycloaddition. / Yu, Jhen Kuei; Chien, Han Wei; Lin, Yi Jung; Karanam, Praneeth; Chen, Yu Heng; Lin, Wenwei.

In: Chemical Communications, Vol. 54, No. 71, 01.01.2018, p. 9921-9924.

Research output: Contribution to journalArticle

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AU - Lin, Wenwei

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