Diversity-oriented synthesis of chromenopyrrolidines from azomethine ylides and 2-hydroxybenzylidene indandiones via base-controlled regiodivergent (3+2) cycloaddition

Jhen Kuei Yu, Han Wei Chien, Yi Jung Lin, Praneeth Karanam, Yu Heng Chen, Wenwei Lin

Research output: Contribution to journalArticle

9 Citations (Scopus)


An organobase-directed, regiodivergent 1,3-dipolar cycloaddition of azomethine ylides and 2-hydoxybenzylidene indandiones is reported. The scarcely explored reversal of the nucleophilic site in azomethine ylides has been exploited for their regiodivergent (3+2) cycloaddition, which subsequently resulted in two different cascade processes to generate functionally distinct chromenopyrrolidines in a diversity oriented manner.

Original languageEnglish
Pages (from-to)9921-9924
Number of pages4
JournalChemical Communications
Issue number71
Publication statusPublished - 2018 Jan 1


ASJC Scopus subject areas

  • Catalysis
  • Electronic, Optical and Magnetic Materials
  • Ceramics and Composites
  • Chemistry(all)
  • Surfaces, Coatings and Films
  • Metals and Alloys
  • Materials Chemistry

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