Direct structural determination of conformations of photoswitchable molecules by laser desorption-electron diffraction

Andreas Gahlmann; I. Ren Lee; Ahmed H. Zewail

doi:10.1002/anie.201003583

Direct structural determination of conformations of photoswitchable molecules by laser desorption-electron diffraction

Andreas Gahlmann, I. Ren Lee, Ahmed H. Zewail

Department of Chemistry

Research output: Contribution to journal › Article

18 Citations (Scopus)

Abstract

Fluorine in charge! The fluorine-iminium ion gauche effect has been exploited in the design of conformational probes for organocatalysis (see scheme). Stabilizing hyperconjugative [σ C- H→σ^*C-F] and/or electrostatic [N⁺ F ^δ-] interactions render the C-F bond an excellent steering group for controlling molecular topology without introducing additional steric constraints.

Original language	English
Pages (from-to)	6524-6527
Number of pages	4
Journal	Angewandte Chemie - International Edition
Volume	49
Issue number	37
DOIs	https://doi.org/10.1002/anie.201003583
Publication status	Published - 2010 Sep 3

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Keywords

Conformational analysis
Density functional calculations
Electron diffraction
Laser desorption
Photochromism

ASJC Scopus subject areas

Catalysis
Chemistry(all)

Cite this

Gahlmann, A., Lee, I. R., & Zewail, A. H. (2010). Direct structural determination of conformations of photoswitchable molecules by laser desorption-electron diffraction. Angewandte Chemie - International Edition, 49(37), 6524-6527. https://doi.org/10.1002/anie.201003583

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Access to Document

10.1002/anie.201003583