Direct-growth of polyaniline nanowires for enzyme-immobilization and glucose detection

Ying Ying Horng, Yu Kuei Hsu, Abhijit Ganguly, Chia Chun Chen, Li Chyong Chen*, Kuei Hsien Chen

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

67 Citations (Scopus)


Amperometric enzyme biosensor based on the glucose oxidase (GOx) incorporated polyaniline nanowires (PANI-NWs) on carbon cloth (CC) electrode was demonstrated. The simple, direct-growth of PANI-NWs on CC, via electrochemical polymerization, provides free-standing, template-independent, hence almost (interfacial) defects-free nanostructures. The defect-free interfaces, along with the excellently sensitive organic nanostructured-surface, as evident from its significantly large effective surface area (24 times the geometric area) for redox-sensing, allows efficient entrapment/immobilization and sensing of biomolecules, via rapid electron-transfer at NWs-CC. The GOx-immobilized PANI-NWs/CC, even in initial unoptimized stage, exhibited an excellent sensitivity, ∼2.5 mA mM-1 cm-2, to glucose, over detection range 0-8 mM, adequate for clinical monitoring of human glucose levels. The report clearly reveals a cost-effective simple system possessing enormous potentiality for biosensors, bioenergy and bioelectronics applications.

Original languageEnglish
Pages (from-to)850-853
Number of pages4
JournalElectrochemistry Communications
Issue number4
Publication statusPublished - 2009 Apr


  • Electrochemical polymerization
  • Glucose biosensor
  • Glucose oxidase
  • Nerstian behavior
  • Polyaniline (PANI) nanowires

ASJC Scopus subject areas

  • Electrochemistry


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