Direct-growth of polyaniline nanowires for enzyme-immobilization and glucose detection

Ying Ying Horng, Yu Kuei Hsu, Abhijit Ganguly, Chia Chun Chen, Li Chyong Chen, Kuei Hsien Chen

Research output: Contribution to journalArticle

54 Citations (Scopus)

Abstract

Amperometric enzyme biosensor based on the glucose oxidase (GOx) incorporated polyaniline nanowires (PANI-NWs) on carbon cloth (CC) electrode was demonstrated. The simple, direct-growth of PANI-NWs on CC, via electrochemical polymerization, provides free-standing, template-independent, hence almost (interfacial) defects-free nanostructures. The defect-free interfaces, along with the excellently sensitive organic nanostructured-surface, as evident from its significantly large effective surface area (24 times the geometric area) for redox-sensing, allows efficient entrapment/immobilization and sensing of biomolecules, via rapid electron-transfer at NWs-CC. The GOx-immobilized PANI-NWs/CC, even in initial unoptimized stage, exhibited an excellent sensitivity, ∼2.5 mA mM-1 cm-2, to glucose, over detection range 0-8 mM, adequate for clinical monitoring of human glucose levels. The report clearly reveals a cost-effective simple system possessing enormous potentiality for biosensors, bioenergy and bioelectronics applications.

Original languageEnglish
Pages (from-to)850-853
Number of pages4
JournalElectrochemistry Communications
Volume11
Issue number4
DOIs
Publication statusPublished - 2009 Apr 1

Fingerprint

Enzyme immobilization
Polyaniline
Nanowires
Glucose
Carbon
Glucose Oxidase
Glucose oxidase
Biosensors
Defects
Electropolymerization
Biomolecules
Nanostructures
Enzymes
Electrodes
polyaniline
Electrons
Monitoring
Costs

Keywords

  • Electrochemical polymerization
  • Glucose biosensor
  • Glucose oxidase
  • Nerstian behavior
  • Polyaniline (PANI) nanowires

ASJC Scopus subject areas

  • Electrochemistry

Cite this

Direct-growth of polyaniline nanowires for enzyme-immobilization and glucose detection. / Horng, Ying Ying; Hsu, Yu Kuei; Ganguly, Abhijit; Chen, Chia Chun; Chen, Li Chyong; Chen, Kuei Hsien.

In: Electrochemistry Communications, Vol. 11, No. 4, 01.04.2009, p. 850-853.

Research output: Contribution to journalArticle

Horng, Ying Ying ; Hsu, Yu Kuei ; Ganguly, Abhijit ; Chen, Chia Chun ; Chen, Li Chyong ; Chen, Kuei Hsien. / Direct-growth of polyaniline nanowires for enzyme-immobilization and glucose detection. In: Electrochemistry Communications. 2009 ; Vol. 11, No. 4. pp. 850-853.
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