Direct β-acylation of 2-arylidene-1,3-indandiones with acyl chlorides catalyzed by organophosphanes

Chia Jui Lee, Chia Ning Sheu, Cheng Che Tsai, Zong Ze Wu, Wenwei Lin

Research output: Contribution to journalArticle

15 Citations (Scopus)


We have developed an organophosphane-catalyzed direct β-acylation of a series of conjugated systems bearing ketone, amide and ester functionalities using acyl chlorides as trapping reagents. A wide variety of highly functional ketone derivatives were generated efficiently under very mild conditions with high yields according to our protocol. Our adducts can even be utilized as important building blocks for the synthesis of functional tri/tetracyclic pyridazine derivatives.

Original languageEnglish
Pages (from-to)5304-5306
Number of pages3
JournalChemical Communications
Issue number40
Publication statusPublished - 2014 May 25


ASJC Scopus subject areas

  • Catalysis
  • Electronic, Optical and Magnetic Materials
  • Ceramics and Composites
  • Chemistry(all)
  • Surfaces, Coatings and Films
  • Metals and Alloys
  • Materials Chemistry

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