Diastereoselective three component reaction of N-glyoxyloyl camphorpyrazolidinone, amine and allyltributylstannane: Facile synthesis of homoallylic amines

Chih Liang Chang, Kwun Min Chen

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Diastereoselective allylation of imine derived from N-glyoxyloyl camphorpyrazolidinone and amines was treated with allyltributylstannane in the presence of triflic acid. The corresponding optically enriched homoallylic amines were obtained in reasonable to high material yields and with practical levels of stereoselectivity in 10 min at ambient temperature.

Original languageEnglish
Pages (from-to)1591-1594
Number of pages4
JournalJournal of the Chinese Chemical Society
Volume54
Issue number6
DOIs
Publication statusPublished - 2007 Jan 1

Keywords

  • Allylation
  • Camphorpyrazolidinone
  • Chiral auxiliary
  • Diastereoselective
  • Homoallylic amine
  • Stereoselectivity

ASJC Scopus subject areas

  • Chemistry(all)

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