Abstract
Spirolactones, spirotetrahydrofurans, and spiropyrrolidines containing a vicinal cis-diol adjacent to the spiro-carbon center are prepared by one-pot epoxidation/spirocyclization of cyclohex-2-en-1-ols bearing an ester, alcohol, or amide functional side chain at the C(3) position of the ring.
| Original language | English |
|---|---|
| Pages (from-to) | 3393-3399 |
| Number of pages | 7 |
| Journal | Organic and Biomolecular Chemistry |
| Volume | 11 |
| Issue number | 20 |
| DOIs | |
| Publication status | Published - 2013 May 28 |
ASJC Scopus subject areas
- Biochemistry
- Physical and Theoretical Chemistry
- Organic Chemistry
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Cite this
Yeh, M. C. P., Liang, C. J., Liu, C. Y., Shih, Y. F., Lee, I. C., Liu, H. F., & Wang, J. L. (2013). Diastereoselective synthesis of vicinal cis-dihydroxyheterospirocycles by one-pot epoxidation/spirocyclization of C(3)-functionalized cyclohex-2-en-1-ols. Organic and Biomolecular Chemistry, 11(20), 3393-3399. https://doi.org/10.1039/c3ob27352k