Determination of three endocrine disrupting chemicals, triclosan, 4-n-nonylphenol, and di-n-butyl phthalate using stir bar sorptive extraction in samples of different matrices

Matt S. Chang, Jermiah Y. Shen, Sheng Hsiung Yang, Gaston J. Wu

Research output: Contribution to journalArticle

8 Citations (Scopus)


Three endocrine disrupting chemicals (EDCs), triclosan (TCS), 4-n-nonylphenol (4-n-NP), and di-n-butyl phthalate (DBP) were determined using stir bar sorptive extraction (SBSE) along with high-performance liquid chromatography/photodiode array detection (HPLC/DAD). Benzyl butyl phthalate was used as an internal standard. The targeted analytes could be rapidly determined with limits of quantification (LOQ) ranging from 4.1 (DBP), 10 (TCS), to 34 (4-n-NP) μg L-1 in real samples such as bottled waters, personal care products, soaps, lotions, and urine. The results show that the developed analytical scheme is solvent-saving, efficient, and capable of fast screening samples for these common EDCs.

Original languageEnglish
Pages (from-to)1027-1033
Number of pages7
JournalToxicological and Environmental Chemistry
Issue number6
Publication statusPublished - 2012 Jul 1



  • SBSE
  • endocrine disrupting chemicals
  • nonylphenol
  • phthalate esters
  • triclosan

ASJC Scopus subject areas

  • Environmental Chemistry
  • Pollution
  • Health, Toxicology and Mutagenesis

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