TY - JOUR
T1 - Deprotonation and reductive addition reactions of hypervalent aluminium dihydride compounds containing substituted pyrrolyl ligands with phenols, ketones, and aldehydes
AU - Chen, I. Chun
AU - Ho, Shi Mau
AU - Chen, Ya Chi
AU - Lin, Che Yu
AU - Hu, Ching Han
AU - Tu, Cheng Yi
AU - Datta, Amitabha
AU - Huang, Jui Hsien
AU - Lin, Chia Her
PY - 2009/10/28
Y1 - 2009/10/28
N2 - The reactivities of [C4H2N(CH2NMe 2)2]AlH2 (1) with primary and secondary amines, phenols, ketones, and phenyl isothiocyanate were examined. Reactions of 1 with one or two equivalents of 2,6-dichloroaniline in methylene chloride generated [C4H2N(CH2NMe2)2] AlH(NHC6H3-2,6-Cl2) (2) and [C 4H2N(CH2NMe2)2] Al(NHC6H3-2,6-Cl2)2 (3), respectively, following hydrogen elimination. Similarly, the reactions of 1 with one or two equivalents of carbazole afforded [C4H 2N(CH2NMe2)2]AlH(NC 12H8) (4) or [C4H2N(CH 2NMe2)2]Al(NC12H8) 2 (5) by deprotonating the acidic N-H of carbazole. Reacting 1 with one equivalent of 2,6-diisopropylphenol in diethyl ether formed an aluminium phenoxo compound [C4H2N(CH2NMe 2)2]AlH(OC6H3-2,6- iPr2) (6), by deprotonation of phenol as well with the elimination of one equivalent hydrogen. Further reaction of 6 with one equivalent of 2,4,6-trimethylacetophenone in methylene chloride generated [C4H2N(CH2NMe2)2] Al(OC6H3-2,6-iPr2)[OC(CH 2)(C6H2-2,4,6-Me3)] (7) by deprotonating the methyl proton of the acetophenone. Similar deprotonation occurred when 1 reacted with two equivalents of 2,4,6-trimethylacetophenone in methylene chloride to generate [C4H2N(CH 2NMe2)2]Al[OC(CH2)(C 6H2-2,4,6-Me3)]2 (8). Compounds [C4H2N(CH2NMe2)2] Al(OCHPh2)2 (9), and [C4H2N(CH 2NMe2)2]Al(SCHNPh)2 (10) could also be obtained by reacting 1 with two equivalents of benzophenone and phenyl isothiocyanate, respectively through hydroalumination. The 1H NMR spectra of 10 showed broad signals for the CH2N and NMe2 groups, which represent dynamical fluctuations of the molecules in solution state. The estimated energy barrier (ΔGc‡) from the coalescence temperature for the fluctuation was estimated at 17.1 Kcal mol-1. The solid-state structures of compounds 2, 3, 5, 7, 9, and 10 have been determined.
AB - The reactivities of [C4H2N(CH2NMe 2)2]AlH2 (1) with primary and secondary amines, phenols, ketones, and phenyl isothiocyanate were examined. Reactions of 1 with one or two equivalents of 2,6-dichloroaniline in methylene chloride generated [C4H2N(CH2NMe2)2] AlH(NHC6H3-2,6-Cl2) (2) and [C 4H2N(CH2NMe2)2] Al(NHC6H3-2,6-Cl2)2 (3), respectively, following hydrogen elimination. Similarly, the reactions of 1 with one or two equivalents of carbazole afforded [C4H 2N(CH2NMe2)2]AlH(NC 12H8) (4) or [C4H2N(CH 2NMe2)2]Al(NC12H8) 2 (5) by deprotonating the acidic N-H of carbazole. Reacting 1 with one equivalent of 2,6-diisopropylphenol in diethyl ether formed an aluminium phenoxo compound [C4H2N(CH2NMe 2)2]AlH(OC6H3-2,6- iPr2) (6), by deprotonation of phenol as well with the elimination of one equivalent hydrogen. Further reaction of 6 with one equivalent of 2,4,6-trimethylacetophenone in methylene chloride generated [C4H2N(CH2NMe2)2] Al(OC6H3-2,6-iPr2)[OC(CH 2)(C6H2-2,4,6-Me3)] (7) by deprotonating the methyl proton of the acetophenone. Similar deprotonation occurred when 1 reacted with two equivalents of 2,4,6-trimethylacetophenone in methylene chloride to generate [C4H2N(CH 2NMe2)2]Al[OC(CH2)(C 6H2-2,4,6-Me3)]2 (8). Compounds [C4H2N(CH2NMe2)2] Al(OCHPh2)2 (9), and [C4H2N(CH 2NMe2)2]Al(SCHNPh)2 (10) could also be obtained by reacting 1 with two equivalents of benzophenone and phenyl isothiocyanate, respectively through hydroalumination. The 1H NMR spectra of 10 showed broad signals for the CH2N and NMe2 groups, which represent dynamical fluctuations of the molecules in solution state. The estimated energy barrier (ΔGc‡) from the coalescence temperature for the fluctuation was estimated at 17.1 Kcal mol-1. The solid-state structures of compounds 2, 3, 5, 7, 9, and 10 have been determined.
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U2 - 10.1039/b908164j
DO - 10.1039/b908164j
M3 - Article
C2 - 19809740
AN - SCOPUS:74249097068
SN - 1477-9226
SP - 8631
EP - 8643
JO - Dalton Transactions
JF - Dalton Transactions
IS - 40
ER -