CuI-Catalyzed intramolecular aminocyanation of terminal alkynes in N-(2-ethynylphenyl)-N-sulfonylcyanamides via Cu-vinylidene intermediates

Zhen Yuan Liao, Pen Yuan Liao, Tun-Cheng Chien

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

CuI-Catalyzed intramolecular aminocyanation of terminal alkynes in N-(2-ethynylphenyl)-N-sulfonylcyanamides was initiated by the formation of Cu-acetylide to trigger N-CN bond cleavage of the N-sulfonylcyanamide moiety followed by CN migration to form a β-cyano Cu-vinylidene intermediate. Subsequently, the indole ring closure furnished the corresponding 1-sulfonyl-3-cyanoindoles.

Original languageEnglish
Pages (from-to)14404-14407
Number of pages4
JournalChemical Communications
Volume52
Issue number100
DOIs
Publication statusPublished - 2016 Jan 1

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Alkynes
indole
3-cyanoindole

ASJC Scopus subject areas

  • Catalysis
  • Electronic, Optical and Magnetic Materials
  • Ceramics and Composites
  • Chemistry(all)
  • Surfaces, Coatings and Films
  • Metals and Alloys
  • Materials Chemistry

Cite this

CuI-Catalyzed intramolecular aminocyanation of terminal alkynes in N-(2-ethynylphenyl)-N-sulfonylcyanamides via Cu-vinylidene intermediates. / Liao, Zhen Yuan; Liao, Pen Yuan; Chien, Tun-Cheng.

In: Chemical Communications, Vol. 52, No. 100, 01.01.2016, p. 14404-14407.

Research output: Contribution to journalArticle

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