Copper(I)-catalyzed aerobic oxidative azide-alkene cyclo-addition: An efficient synthesis of substituted 1,2,3-triazoles

Donala Janreddy; Veerababurao Kavala; Chun Wei Kuo; Wen Chang Chen; Chintakunta Ramesh; Trimurtulu Kotipalli; Ting Shen Kuo; Mei Ling Chen; Chiu Hui He; Ching Fa Yao

doi:10.1002/adsc.201300344

Copper(I)-catalyzed aerobic oxidative azide-alkene cyclo-addition: An efficient synthesis of substituted 1,2,3-triazoles

Donala Janreddy, Veerababurao Kavala, Chun Wei Kuo, Wen Chang Chen, Chintakunta Ramesh, Trimurtulu Kotipalli, Ting Shen Kuo, Mei Ling Chen, Chiu Hui He, Ching Fa Yao^*

^*Corresponding author for this work

Department of Chemistry

Research output: Contribution to journal › Article › peer-review

52 Citations (Scopus)

Abstract

A novel, copper(I)-promoted azide-alkene aerobic oxidative cycloaddition protocol was devel-oped for the regioselective synthesis of 1,4-disubsti-tuted/ 1,4,5-trisubstituted 1,2,3-triazoles by using azides and electron-deficient olefins under an oxygen atmosphere.

Original language	English
Pages (from-to)	2918-2927
Number of pages	10
Journal	Advanced Synthesis and Catalysis
Volume	355
Issue number	14-15
DOIs	https://doi.org/10.1002/adsc.201300344
Publication status	Published - 2013 Oct 11

Keywords

1 2 3-triazoles
Aerobic oxidation
Azide-alkene cycload-dition
Copper catalysis

ASJC Scopus subject areas

Catalysis
Organic Chemistry

Access to Document

10.1002/adsc.201300344

Cite this

@article{ef8753435f174a3ea84ae1ec148f49ed,

title = "Copper(I)-catalyzed aerobic oxidative azide-alkene cyclo-addition: An efficient synthesis of substituted 1,2,3-triazoles",

abstract = "A novel, copper(I)-promoted azide-alkene aerobic oxidative cycloaddition protocol was devel-oped for the regioselective synthesis of 1,4-disubsti-tuted/ 1,4,5-trisubstituted 1,2,3-triazoles by using azides and electron-deficient olefins under an oxygen atmosphere.",

keywords = "1 2 3-triazoles, Aerobic oxidation, Azide-alkene cycload-dition, Copper catalysis",

author = "Donala Janreddy and Veerababurao Kavala and Kuo, {Chun Wei} and Chen, {Wen Chang} and Chintakunta Ramesh and Trimurtulu Kotipalli and Kuo, {Ting Shen} and Chen, {Mei Ling} and He, {Chiu Hui} and Yao, {Ching Fa}",

year = "2013",

month = oct,

day = "11",

doi = "10.1002/adsc.201300344",

language = "English",

volume = "355",

pages = "2918--2927",

journal = "Advanced Synthesis and Catalysis",

issn = "1615-4150",

publisher = "Wiley-VCH Verlag",

number = "14-15",

}

TY - JOUR

T1 - Copper(I)-catalyzed aerobic oxidative azide-alkene cyclo-addition

T2 - An efficient synthesis of substituted 1,2,3-triazoles

AU - Janreddy, Donala

AU - Kavala, Veerababurao

AU - Kuo, Chun Wei

AU - Chen, Wen Chang

AU - Ramesh, Chintakunta

AU - Kotipalli, Trimurtulu

AU - Kuo, Ting Shen

AU - Chen, Mei Ling

AU - He, Chiu Hui

AU - Yao, Ching Fa

PY - 2013/10/11

Y1 - 2013/10/11

N2 - A novel, copper(I)-promoted azide-alkene aerobic oxidative cycloaddition protocol was devel-oped for the regioselective synthesis of 1,4-disubsti-tuted/ 1,4,5-trisubstituted 1,2,3-triazoles by using azides and electron-deficient olefins under an oxygen atmosphere.

AB - A novel, copper(I)-promoted azide-alkene aerobic oxidative cycloaddition protocol was devel-oped for the regioselective synthesis of 1,4-disubsti-tuted/ 1,4,5-trisubstituted 1,2,3-triazoles by using azides and electron-deficient olefins under an oxygen atmosphere.

KW - 1 2 3-triazoles

KW - Aerobic oxidation

KW - Azide-alkene cycload-dition

KW - Copper catalysis

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DO - 10.1002/adsc.201300344

M3 - Article

AN - SCOPUS:84895152983

SN - 1615-4150

VL - 355

SP - 2918

EP - 2927

JO - Advanced Synthesis and Catalysis

JF - Advanced Synthesis and Catalysis

IS - 14-15

ER -

Copper(I)-catalyzed aerobic oxidative azide-alkene cyclo-addition: An efficient synthesis of substituted 1,2,3-triazoles

Abstract

Keywords

ASJC Scopus subject areas

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CCDC 922119: Experimental Crystal Structure Determination

CCDC 922121: Experimental Crystal Structure Determination

CCDC 922122: Experimental Crystal Structure Determination

Cite this

Copper(I)-catalyzed aerobic oxidative azide-alkene cyclo-addition: An efficient synthesis of substituted 1,2,3-triazoles

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Datasets

CCDC 922119: Experimental Crystal Structure Determination

CCDC 922121: Experimental Crystal Structure Determination

CCDC 922122: Experimental Crystal Structure Determination

Cite this