Copper(I)-catalyzed aerobic oxidative azide-alkene cyclo-addition: An efficient synthesis of substituted 1,2,3-triazoles

Donala Janreddy, Veerababurao Kavala, Chun Wei Kuo, Wen Chang Chen, Chintakunta Ramesh, Trimurtulu Kotipalli, Ting Shen Kuo, Mei Ling Chen, Chiu Hui He, Ching Fa Yao

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32 Citations (Scopus)

Abstract

A novel, copper(I)-promoted azide-alkene aerobic oxidative cycloaddition protocol was devel-oped for the regioselective synthesis of 1,4-disubsti-tuted/ 1,4,5-trisubstituted 1,2,3-triazoles by using azides and electron-deficient olefins under an oxygen atmosphere.

Original languageEnglish
Pages (from-to)2918-2927
Number of pages10
JournalAdvanced Synthesis and Catalysis
Volume355
Issue number14-15
DOIs
Publication statusPublished - 2013 Jan 1

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Keywords

  • 1 2 3-triazoles
  • Aerobic oxidation
  • Azide-alkene cycload-dition
  • Copper catalysis

ASJC Scopus subject areas

  • Catalysis
  • Organic Chemistry

Cite this

Janreddy, D., Kavala, V., Kuo, C. W., Chen, W. C., Ramesh, C., Kotipalli, T., Kuo, T. S., Chen, M. L., He, C. H., & Yao, C. F. (2013). Copper(I)-catalyzed aerobic oxidative azide-alkene cyclo-addition: An efficient synthesis of substituted 1,2,3-triazoles. Advanced Synthesis and Catalysis, 355(14-15), 2918-2927. https://doi.org/10.1002/adsc.201300344