Construction of indeno[1,2-b]pyrrolesviachemoselectiveN-acylation/cyclization/Wittig reaction sequence

Athukuri Edukondalu, Sandip Sambhaji Vagh, Ting Han Lin, Wenwei Lin

Research output: Contribution to journalArticlepeer-review

1 Citation (Scopus)

Abstract

An efficient protocol for the chemoselective construction of the indeno[1,2-b]pyrroles and rearranged indeno[1,2-b]pyrrole derivatives is reportedviaanN-acylation/cyclization/Wittig reaction. Extensive mechanistic investigations revealed that the initially formed crucial spiro-indene-1,2′-[1,3,4]oxadiazol intermediate further reacts with phosphine to generate betaine, thus predominately resulting in the aforementioned heteroarenes proceeding by a Wittig reaction.

Original languageEnglish
Pages (from-to)2045-2048
Number of pages4
JournalChemical Communications
Volume57
Issue number16
DOIs
Publication statusPublished - 2021 Feb 25

ASJC Scopus subject areas

  • Catalysis
  • Electronic, Optical and Magnetic Materials
  • Ceramics and Composites
  • Chemistry(all)
  • Surfaces, Coatings and Films
  • Metals and Alloys
  • Materials Chemistry

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