Confined multilamellae prefer cylindrical morphology: AAAA theory of myelin formation

J. R. Huang, L. N. Zou, T. A. Witten

Research output: Contribution to journalArticle

27 Citations (Scopus)

Abstract

By evaporating a drop of lipid dispersion we generate the myelin morphology often seen in dissolving surfactant powders. We explain these puzzling nonequilibrium structures using a geometric argument: the bilayer repeat spacing increases and thus the repulsion between bilayers decreases when a multilamellar disk is converted into a myelin without gain or loss of material and with number of bilayers unchanged. Sufficient reduction in bilayer repulsion can compensate for the cost in curvature energy, leading to a net stability of the myelin structure. A numerical estimate predicts the degree of dehydration required to favor myelin structures over flat lamellae.

Original languageEnglish
Pages (from-to)279-285
Number of pages7
JournalEuropean Physical Journal E
Volume18
Issue number3
DOIs
Publication statusPublished - 2005 Nov 1

Fingerprint

myelin
Myelin Sheath
Dehydration
Surface-Active Agents
Powders
Lipids
Surface active agents
Costs
lamella
dehydration
lipids
dissolving
surfactants
curvature
spacing
costs
Costs and Cost Analysis
estimates
energy

ASJC Scopus subject areas

  • Biotechnology
  • Biophysics
  • Chemistry(all)
  • Materials Science(all)
  • Surfaces and Interfaces

Cite this

Confined multilamellae prefer cylindrical morphology : AAAA theory of myelin formation. / Huang, J. R.; Zou, L. N.; Witten, T. A.

In: European Physical Journal E, Vol. 18, No. 3, 01.11.2005, p. 279-285.

Research output: Contribution to journalArticle

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