Comparison of gampi paper and nanofibers to chromatography paper used in paper spray-mass spectrometry

Pei Hua Lai, Pei Chun Chen, Ya Wei Liao, Ju Tsung Liu, Chien Chung Chen*, Cheng Huang Lin

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

25 Citations (Scopus)


Two series of "papers" that were made from natural fibers and synthetic fibers, respectively, were examined for use in paper-spray mass spectrometry and the results were compared to chromatography paper that is currently being used. In the former case, four types of papers were used, including gampi paper, tengujou paper, glassine paper and cicada paper, and the findings show that the limit of detection can be improved when gampi paper was used. This is because gampi paper is very tough and extremely thin (thickness, <20 μm), which permits sample molecules to be translated and evaporated nearly instantly. Since ionization occurs within a very short period, an abundance of ions is formed, leading to a dramatic improvement in the limit of detection. Meanwhile, a series of tough, thin synthetic fibers, including a microarray membrane (hollow and fibrous) and nanofibers, were also tested. The papers were prepared from polycarbonate, polylactic acid and poly-L-lactic acid (PLLA), respectively, by means of a co-axial electrospinning technique. The findings show that the limit of detection also can be improved, when a PLLA nanofiber was used. This is because this type of paper-like nanofiber is also very thin, tough and hydrophobic, which permits to ionization to occur within a very short period. Detailed information on methods for synthesizing these fibers and their use in the analysis of a real sample are also reported.

Original languageEnglish
Pages (from-to)14-17
Number of pages4
JournalInternational Journal of Mass Spectrometry
Publication statusPublished - 2015 Jan 1


  • Gampi paper
  • Microarray membrane
  • Nanofiber
  • Paper spray-mass spectrometry
  • p-Chloroamphetamine

ASJC Scopus subject areas

  • Instrumentation
  • Condensed Matter Physics
  • Spectroscopy
  • Physical and Theoretical Chemistry


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