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Chronic low dose of AM404 ameliorates the cognitive impairment and pathological features in hyperglycemic 3xTg-AD mice
Hei Jen Huang
, Shu Ling Chen
, Hsin Yu Huang
,
Ying Chieh Sun
, Guan Chiun Lee
,
Guey Jen Lee-Chen
,
Hsiu Mei Hsieh-Li
*
,
Ming Tsan Su
*
Corresponding author for this work
Department of Chemistry
Department of Life Science
Research output
:
Contribution to journal
›
Article
›
peer-review
16
Citations (Scopus)
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Dive into the research topics of 'Chronic low dose of AM404 ameliorates the cognitive impairment and pathological features in hyperglycemic 3xTg-AD mice'. Together they form a unique fingerprint.
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INIS
doses
100%
nervous system diseases
100%
mice
100%
inflammation
22%
hyperglycemia
22%
learning
11%
water
11%
production
11%
proteins
11%
administration
11%
in vitro
11%
in vivo
11%
brain
11%
inhibition
11%
hippocampus
11%
plasticity
11%
phosphorylation
11%
chronic administration
11%
Neuroscience
Cognitive Disorders
100%
AM404
100%
Alzheimer's Disease
100%
Primary Culture
16%
Neuroprotection
16%
Hyperglycemia
16%
Hyperphosphorylation
16%
Hippocampus
8%
Synaptic Plasticity
8%
In Vivo
8%
Tau Protein
8%
Water Maze
8%
Wortmannin
8%
In Vitro
8%
Protein Phosphorylation
8%
Mouse Brain
8%
Medicine and Dentistry
Primary Culture
16%
IC50
8%
Pharmacology, Toxicology and Pharmaceutical Science
Wortmannin
8%
Systemic Administration
8%
Tau Protein
8%