Catalyst free conjugate addition of indoles and pyrroles to nitro alkenes under solvent free condition (SFC): An effective greener route to access 3-(2-nitro-1-phenylethyl)-1H-indole and 2-(2-nitro-1-phenylethyl)-1H-pyrrole derivatives

Pateliya Mujjamil Habib; Veerababurao Kavala; Chun Wei Kuo; Mustafa J. Raihan; Ching Fa Yao

doi:10.1016/j.tet.2010.05.104

Catalyst free conjugate addition of indoles and pyrroles to nitro alkenes under solvent free condition (SFC): An effective greener route to access 3-(2-nitro-1-phenylethyl)-1H-indole and 2-(2-nitro-1-phenylethyl)-1H-pyrrole derivatives

Pateliya Mujjamil Habib, Veerababurao Kavala, Chun Wei Kuo, Mustafa J. Raihan, Ching Fa Yao^*

^*Corresponding author for this work

Department of Chemistry

Research output: Contribution to journal › Article › peer-review

32 Citations (Scopus)

Abstract

Catalyst free conjugate addition of reactive hetero aromatics (pyrrole and indoles) to nitro alkenes under solvent free condition is described. This method provides several advantages, such as operational simplicity, solvent-free conditions and good yields of products. Also it is environmentally friendly and more cost effective alternative to existing protocols. Catalyst free conjugate addition of reactive hetero aromatics (pyrrole and indoles) to nitro alkenes under solvent free condition is described. This method provides several advantages, such as operational simplicity, solvent-free conditions and good yields of products. Also it is environmentally friendly and more cost effective alternative to existing protocols.

Original language	English
Pages (from-to)	7050-7056
Number of pages	7
Journal	Tetrahedron
Volume	66
Issue number	34
DOIs	https://doi.org/10.1016/j.tet.2010.05.104
Publication status	Published - 2010 Aug 21

ASJC Scopus subject areas

Biochemistry
Drug Discovery
Organic Chemistry

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Habib, P. M., Kavala, V., Kuo, C. W., Raihan, M. J., & Yao, C. F. (2010). Catalyst free conjugate addition of indoles and pyrroles to nitro alkenes under solvent free condition (SFC): An effective greener route to access 3-(2-nitro-1-phenylethyl)-1H-indole and 2-(2-nitro-1-phenylethyl)-1H-pyrrole derivatives. Tetrahedron, 66(34), 7050-7056. https://doi.org/10.1016/j.tet.2010.05.104

Catalyst free conjugate addition of indoles and pyrroles to nitro alkenes under solvent free condition (SFC): An effective greener route to access 3-(2-nitro-1-phenylethyl)-1H-indole and 2-(2-nitro-1-phenylethyl)-1H-pyrrole derivatives. / Habib, Pateliya Mujjamil; Kavala, Veerababurao; Kuo, Chun Wei et al.
In: Tetrahedron, Vol. 66, No. 34, 21.08.2010, p. 7050-7056.

Research output: Contribution to journal › Article › peer-review

Habib, PM, Kavala, V, Kuo, CW, Raihan, MJ & Yao, CF 2010, 'Catalyst free conjugate addition of indoles and pyrroles to nitro alkenes under solvent free condition (SFC): An effective greener route to access 3-(2-nitro-1-phenylethyl)-1H-indole and 2-(2-nitro-1-phenylethyl)-1H-pyrrole derivatives', Tetrahedron, vol. 66, no. 34, pp. 7050-7056. https://doi.org/10.1016/j.tet.2010.05.104

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title = "Catalyst free conjugate addition of indoles and pyrroles to nitro alkenes under solvent free condition (SFC): An effective greener route to access 3-(2-nitro-1-phenylethyl)-1H-indole and 2-(2-nitro-1-phenylethyl)-1H-pyrrole derivatives",

abstract = "Catalyst free conjugate addition of reactive hetero aromatics (pyrrole and indoles) to nitro alkenes under solvent free condition is described. This method provides several advantages, such as operational simplicity, solvent-free conditions and good yields of products. Also it is environmentally friendly and more cost effective alternative to existing protocols. Catalyst free conjugate addition of reactive hetero aromatics (pyrrole and indoles) to nitro alkenes under solvent free condition is described. This method provides several advantages, such as operational simplicity, solvent-free conditions and good yields of products. Also it is environmentally friendly and more cost effective alternative to existing protocols.",

author = "Habib, {Pateliya Mujjamil} and Veerababurao Kavala and Kuo, {Chun Wei} and Raihan, {Mustafa J.} and Yao, {Ching Fa}",

note = "Funding Information: Financial support of this work by National Science Council of the Republic of China and National Taiwan Normal University is gratefully acknowledged.",

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AU - Habib, Pateliya Mujjamil

AU - Kavala, Veerababurao

AU - Kuo, Chun Wei

AU - Raihan, Mustafa J.

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AB - Catalyst free conjugate addition of reactive hetero aromatics (pyrrole and indoles) to nitro alkenes under solvent free condition is described. This method provides several advantages, such as operational simplicity, solvent-free conditions and good yields of products. Also it is environmentally friendly and more cost effective alternative to existing protocols. Catalyst free conjugate addition of reactive hetero aromatics (pyrrole and indoles) to nitro alkenes under solvent free condition is described. This method provides several advantages, such as operational simplicity, solvent-free conditions and good yields of products. Also it is environmentally friendly and more cost effective alternative to existing protocols.

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Catalyst free conjugate addition of indoles and pyrroles to nitro alkenes under solvent free condition (SFC): An effective greener route to access 3-(2-nitro-1-phenylethyl)-1H-indole and 2-(2-nitro-1-phenylethyl)-1H-pyrrole derivatives

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