Catalyst-free aqueous-mediated conjugative addition of indoles to β-nitrostyrenes

Pateliya Mujjamil Habib, Veerababurao Kavala, Chun Wei Kuo, Ching Fa Yao*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

55 Citations (Scopus)


A catalyst free aqueous-mediated alkylation of indoles with various β-nitrostyrenes was performed at elevated temperature. No catalyst, clean reaction conditions, simple workup procedure, easy isolation, viability for large scale preparation, and environmentally acceptable medium are the best features in this process.

Original languageEnglish
Pages (from-to)7005-7007
Number of pages3
JournalTetrahedron Letters
Issue number49
Publication statusPublished - 2008 Dec 1

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry


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