Catalyst-free aqueous-mediated conjugative addition of indoles to β-nitrostyrenes

Pateliya Mujjamil Habib, Veerababurao Kavala, Chun Wei Kuo, Ching-Fa Yao

Research output: Contribution to journalArticle

53 Citations (Scopus)

Abstract

A catalyst free aqueous-mediated alkylation of indoles with various β-nitrostyrenes was performed at elevated temperature. No catalyst, clean reaction conditions, simple workup procedure, easy isolation, viability for large scale preparation, and environmentally acceptable medium are the best features in this process.

Original languageEnglish
Pages (from-to)7005-7007
Number of pages3
JournalTetrahedron Letters
Volume49
Issue number49
DOIs
Publication statusPublished - 2008 Dec 1

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Indoles
Alkylation
Catalysts
Temperature

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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Catalyst-free aqueous-mediated conjugative addition of indoles to β-nitrostyrenes. / Habib, Pateliya Mujjamil; Kavala, Veerababurao; Kuo, Chun Wei; Yao, Ching-Fa.

In: Tetrahedron Letters, Vol. 49, No. 49, 01.12.2008, p. 7005-7007.

Research output: Contribution to journalArticle

Habib, Pateliya Mujjamil ; Kavala, Veerababurao ; Kuo, Chun Wei ; Yao, Ching-Fa. / Catalyst-free aqueous-mediated conjugative addition of indoles to β-nitrostyrenes. In: Tetrahedron Letters. 2008 ; Vol. 49, No. 49. pp. 7005-7007.
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