Abstract
1,3-Dipolar cycloaddition of 3-nitrochromen with sodium azide under catalyst-free conditions afforded 4-aryl-1,4-dihydrochromeno[4,3-d][1,2,3]triazole derivatives at 80 °C in DMSO is described. The generality of this reaction was demonstrated by synthesizing an array of 4-aryl-1,4-dihydrochromeno[4,3-d][1,2,3]triazole derivatives. Clean reaction conditions, easy isolation, and good yields of the triazoles are the salient features of the methodology.
| Original language | English |
|---|---|
| Pages (from-to) | 5799-5804 |
| Number of pages | 6 |
| Journal | Tetrahedron |
| Volume | 65 |
| Issue number | 29-30 |
| DOIs | |
| Publication status | Published - 2009 Jul 18 |
ASJC Scopus subject areas
- Biochemistry
- Drug Discovery
- Organic Chemistry
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Dive into the research topics of 'Catalyst-free 1,3-dipolar cycloaddition of 3-nitrochromen with sodium azide: a facile method for the synthesis of 4-aryl-1,4-dihydrochromeno[4,3-d][1,2,3]triazole derivatives'. Together they form a unique fingerprint.Datasets
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CCDC 720916: Experimental Crystal Structure Determination
Habib, P. M. (Creator), Rama Raju, R. B. (Contributor), Kavala, V. (Creator), Kuo, C.-W. (Creator) & Yao, C.-F. (Creator), Unknown Publisher, 2010
DOI: 10.5517/ccs65ch, http://www.ccdc.cam.ac.uk/services/structure_request?id=doi:10.5517/ccs65ch&sid=DataCite
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