CAN and iodine-catalyzed reaction of indole or 1-methylindole with α,β-unsaturated ketone or aldehyde

Shengkai Ko, Chunchi Lin, Zhijay Tu, Yi Fu Wang, Chieh Chieh Wang, Ching Fa Yao

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63 Citations (Scopus)

Abstract

CAN (cerium ammonium nitrate) and iodine can catalyze the reactions of indole or 1-methylindole with α,β-unsaturated ketone or aldehyde in DMSO/H2O (5:1) or ether solution at room temperature to obtain moderate to high yields of different products.

Original languageEnglish
Pages (from-to)487-492
Number of pages6
JournalTetrahedron Letters
Volume47
Issue number4
DOIs
Publication statusPublished - 2006 Jan 23

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Keywords

  • CAN
  • Catalyzed
  • Indole
  • Iodine
  • Trisindolylalkane

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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