CAN and iodine-catalyzed reaction of indole or 1-methylindole with α,β-unsaturated ketone or aldehyde

Shengkai Ko, Chunchi Lin, Zhijay Tu, Yi Fu Wang, Chieh Chieh Wang, Ching Fa Yao

Research output: Contribution to journalArticle

62 Citations (Scopus)

Abstract

CAN (cerium ammonium nitrate) and iodine can catalyze the reactions of indole or 1-methylindole with α,β-unsaturated ketone or aldehyde in DMSO/H2O (5:1) or ether solution at room temperature to obtain moderate to high yields of different products.

Original languageEnglish
Pages (from-to)487-492
Number of pages6
JournalTetrahedron Letters
Volume47
Issue number4
DOIs
Publication statusPublished - 2006 Jan 23

Fingerprint

Cerium
Dimethyl Sulfoxide
Ketones
Aldehydes
Iodine
Ether
Temperature
1-methylindole
indole
ammonium nitrate
cerium nitrate

Keywords

  • CAN
  • Catalyzed
  • Indole
  • Iodine
  • Trisindolylalkane

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

Cite this

CAN and iodine-catalyzed reaction of indole or 1-methylindole with α,β-unsaturated ketone or aldehyde. / Ko, Shengkai; Lin, Chunchi; Tu, Zhijay; Wang, Yi Fu; Wang, Chieh Chieh; Yao, Ching Fa.

In: Tetrahedron Letters, Vol. 47, No. 4, 23.01.2006, p. 487-492.

Research output: Contribution to journalArticle

Ko, Shengkai ; Lin, Chunchi ; Tu, Zhijay ; Wang, Yi Fu ; Wang, Chieh Chieh ; Yao, Ching Fa. / CAN and iodine-catalyzed reaction of indole or 1-methylindole with α,β-unsaturated ketone or aldehyde. In: Tetrahedron Letters. 2006 ; Vol. 47, No. 4. pp. 487-492.
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