TY - GEN
T1 - Bio-assays using bio-functionalized magnetic nanoparticles
AU - Hong, Chin Yih
AU - Horng, Herng Er
AU - Yang, Hong Chang
AU - Yang, Shieh Yueh
PY - 2008
Y1 - 2008
N2 - Biocompatible magnetic nano-particles show great potential in bio-magnetic applications. In this work, the feasibility of magnetically labeled immunoassay using biocompatible magnetic nanoparticles is investigated. To do this, we study the synthesis technologies for magnetic nanoparticles Fe3O4, as well as the coating of various bio-probes onto the magnetic nanoparticles to detect bio-targets, such as proteins, virus, etc. Furthermore, the measurement, magnetoreduction assay, for the amount of bio-targets are developed. The results show such merits as high-sensitivity, high-specificity, high-convenience for magnetoreduction assays using magnetic nanoparticles. The whole assay platform is promisingly applied to food inspection, environment monitoring, and even human diagnosis.
AB - Biocompatible magnetic nano-particles show great potential in bio-magnetic applications. In this work, the feasibility of magnetically labeled immunoassay using biocompatible magnetic nanoparticles is investigated. To do this, we study the synthesis technologies for magnetic nanoparticles Fe3O4, as well as the coating of various bio-probes onto the magnetic nanoparticles to detect bio-targets, such as proteins, virus, etc. Furthermore, the measurement, magnetoreduction assay, for the amount of bio-targets are developed. The results show such merits as high-sensitivity, high-specificity, high-convenience for magnetoreduction assays using magnetic nanoparticles. The whole assay platform is promisingly applied to food inspection, environment monitoring, and even human diagnosis.
UR - http://www.scopus.com/inward/record.url?scp=81155123721&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=81155123721&partnerID=8YFLogxK
U2 - 10.1115/DETC2008-49503
DO - 10.1115/DETC2008-49503
M3 - Conference contribution
AN - SCOPUS:69949164943
SN - 9780791843284
T3 - Proceedings of the ASME Design Engineering Technical Conference
SP - 719
EP - 722
BT - ASME 2008 International Design Engineering Technical Conferences and Computers and Information in Engineering Conference, IDETC/CIE2008
T2 - ASME 2008 International Design Engineering Technical Conferences and Computers and Information in Engineering Conference, IDETC/CIE2008
Y2 - 3 August 2008 through 6 August 2008
ER -