Bio-assays using bio-functionalized magnetic nanoparticles

Chin Yih Hong, Herng Er Horng, Hong Chang Yang, Shieh Yueh Yang

    Research output: Chapter in Book/Report/Conference proceedingConference contribution

    Abstract

    Biocompatible magnetic nano-particles show great potential in bio-magnetic applications. In this work, the feasibility of magnetically labeled immunoassay using biocompatible magnetic nanoparticles is investigated. To do this, we study the synthesis technologies for magnetic nanoparticles Fe3O4, as well as the coating of various bio-probes onto the magnetic nanoparticles to detect bio-targets, such as proteins, virus, etc. Furthermore, the measurement, magnetoreduction assay, for the amount of bio-targets are developed. The results show such merits as high-sensitivity, high-specificity, high-convenience for magnetoreduction assays using magnetic nanoparticles. The whole assay platform is promisingly applied to food inspection, environment monitoring, and even human diagnosis.

    Original languageEnglish
    Title of host publicationASME 2008 International Design Engineering Technical Conferences and Computers and Information in Engineering Conference, IDETC/CIE2008
    Pages719-722
    Number of pages4
    Volume4
    DOIs
    Publication statusPublished - 2008 Dec 1
    EventASME 2008 International Design Engineering Technical Conferences and Computers and Information in Engineering Conference, IDETC/CIE2008 - Brooklyn, NY, United States
    Duration: 2008 Aug 32008 Aug 6

    Other

    OtherASME 2008 International Design Engineering Technical Conferences and Computers and Information in Engineering Conference, IDETC/CIE2008
    CountryUnited States
    CityBrooklyn, NY
    Period08/8/308/8/6

    ASJC Scopus subject areas

    • Modelling and Simulation
    • Mechanical Engineering
    • Computer Science Applications
    • Computer Graphics and Computer-Aided Design

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  • Cite this

    Hong, C. Y., Horng, H. E., Yang, H. C., & Yang, S. Y. (2008). Bio-assays using bio-functionalized magnetic nanoparticles. In ASME 2008 International Design Engineering Technical Conferences and Computers and Information in Engineering Conference, IDETC/CIE2008 (Vol. 4, pp. 719-722) https://doi.org/10.1115/DETC2008-49503