Bio-assays using bio-functionalized magnetic nanoparticles

Chin Yih Hong, Herng Er Horng, Hong Chang Yang, Shieh Yueh Yang

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Biocompatible magnetic nano-particles show great potential in bio-magnetic applications. In this work, the feasibility of magnetically labeled immunoassay using biocompatible magnetic nanoparticles is investigated. To do this, we study the synthesis technologies for magnetic nanoparticles Fe3O4, as well as the coating of various bio-probes onto the magnetic nanoparticles to detect bio-targets, such as proteins, virus, etc. Furthermore, the measurement, magnetoreduction assay, for the amount of bio-targets arc developed. The results show such merits as high-sensitivity, high-specificity, high-convenience for magnetoreduction assays using magnetic nanoparticles. The whole assay platform is promisingly applied to food inspection, environment monitoring, and even human diagnosis.

Original languageEnglish
Title of host publication2008 Proceedings of the ASME International Design Engineering Technical Conferences and Computers and Information in Engineering Conference, DETC 2008
Pages719-722
Number of pages4
Publication statusPublished - 2009 Nov 23
Event2008 ASME International Design Engineering Technical Conferences and Computers and Information in Engineering Conference, DETC 2008 - New York City, NY, United States
Duration: 2008 Aug 32008 Aug 6

Publication series

Name2008 Proceedings of the ASME International Design Engineering Technical Conferences and Computers and Information in Engineering Conference, DETC 2008
Volume4

Other

Other2008 ASME International Design Engineering Technical Conferences and Computers and Information in Engineering Conference, DETC 2008
CountryUnited States
CityNew York City, NY
Period08/8/308/8/6

ASJC Scopus subject areas

  • Artificial Intelligence
  • Computational Theory and Mathematics
  • Industrial and Manufacturing Engineering
  • Mechanical Engineering

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  • Cite this

    Hong, C. Y., Horng, H. E., Yang, H. C., & Yang, S. Y. (2009). Bio-assays using bio-functionalized magnetic nanoparticles. In 2008 Proceedings of the ASME International Design Engineering Technical Conferences and Computers and Information in Engineering Conference, DETC 2008 (pp. 719-722). (2008 Proceedings of the ASME International Design Engineering Technical Conferences and Computers and Information in Engineering Conference, DETC 2008; Vol. 4).