BF3·OEt2-mediated one pot synthesis of 10-indolyldibenzo[b,f]azepine derivatives via tandem ring expansion and C-C bond formation

Trimurtulu Kotipalli; Donala Janreddy; Veerababurao Kavala; Chun Wei Kuo; Ting Shen Kuo; Mei Ling Chen; Chiu Hui He; Ching Fa Yao

doi:10.1039/c4ra08723b

BF₃·OEt₂-mediated one pot synthesis of 10-indolyldibenzo[b,f]azepine derivatives via tandem ring expansion and C-C bond formation

Trimurtulu Kotipalli, Donala Janreddy, Veerababurao Kavala, Chun Wei Kuo, Ting Shen Kuo, Mei Ling Chen, Chiu Hui He, Ching Fa Yao^*

^*Corresponding author for this work

Department of Chemistry

Research output: Contribution to journal › Article › peer-review

6 Citations (Scopus)

Abstract

A simple and efficient one pot protocol was developed for the synthesis of new structurally diverse 10-indolyldibenzo[b,f]azepine derivatives. The reaction involves Lewis-acid mediated ring expansion followed by C-C bond formation through nucleophilic addition of indole moiety.

Original language	English
Pages (from-to)	47833-47840
Number of pages	8
Journal	RSC Advances
Volume	4
Issue number	88
DOIs	https://doi.org/10.1039/c4ra08723b
Publication status	Published - 2014

ASJC Scopus subject areas

General Chemistry
General Chemical Engineering

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10.1039/c4ra08723b

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title = "BF3·OEt2-mediated one pot synthesis of 10-indolyldibenzo[b,f]azepine derivatives via tandem ring expansion and C-C bond formation",

abstract = "A simple and efficient one pot protocol was developed for the synthesis of new structurally diverse 10-indolyldibenzo[b,f]azepine derivatives. The reaction involves Lewis-acid mediated ring expansion followed by C-C bond formation through nucleophilic addition of indole moiety.",

author = "Trimurtulu Kotipalli and Donala Janreddy and Veerababurao Kavala and Kuo, {Chun Wei} and Kuo, {Ting Shen} and Chen, {Mei Ling} and He, {Chiu Hui} and Yao, {Ching Fa}",

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AU - Kotipalli, Trimurtulu

AU - Janreddy, Donala

AU - Kavala, Veerababurao

AU - Kuo, Chun Wei

AU - Kuo, Ting Shen

AU - Chen, Mei Ling

AU - He, Chiu Hui

AU - Yao, Ching Fa

PY - 2014

Y1 - 2014

N2 - A simple and efficient one pot protocol was developed for the synthesis of new structurally diverse 10-indolyldibenzo[b,f]azepine derivatives. The reaction involves Lewis-acid mediated ring expansion followed by C-C bond formation through nucleophilic addition of indole moiety.

AB - A simple and efficient one pot protocol was developed for the synthesis of new structurally diverse 10-indolyldibenzo[b,f]azepine derivatives. The reaction involves Lewis-acid mediated ring expansion followed by C-C bond formation through nucleophilic addition of indole moiety.

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BF₃·OEt₂-mediated one pot synthesis of 10-indolyldibenzo[b,f]azepine derivatives via tandem ring expansion and C-C bond formation

Abstract

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CCDC 1003566: Experimental Crystal Structure Determination

CCDC 1003565: Experimental Crystal Structure Determination

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BF3·OEt2-mediated one pot synthesis of 10-indolyldibenzo[b,f]azepine derivatives via tandem ring expansion and C-C bond formation

Abstract

ASJC Scopus subject areas

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Datasets

CCDC 1003566: Experimental Crystal Structure Determination

CCDC 1003565: Experimental Crystal Structure Determination

Cite this

BF₃·OEt₂-mediated one pot synthesis of 10-indolyldibenzo[b,f]azepine derivatives via tandem ring expansion and C-C bond formation