Asymmetric synthesis of propargylic alcohols catalyzed by (-)-MITH

Ping Yu Wu, Hsyueh Liang Wu, Ying Ying Shen, Biing Jiun Uang*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

19 Citations (Scopus)


This investigation describes that in the presence of 2.5 mol % of (-)-2-exo-morpholinoisobornane-10-thiol (MITH) 1, catalytic asymmetric alkynylation of aldehydes gives enantioenriched propargylic alcohols with good enantioselectivities.

Original languageEnglish
Pages (from-to)1837-1841
Number of pages5
JournalTetrahedron Asymmetry
Issue number16
Publication statusPublished - 2009 Aug 26
Externally publishedYes

ASJC Scopus subject areas

  • Catalysis
  • Physical and Theoretical Chemistry
  • Organic Chemistry
  • Inorganic Chemistry


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