Asymmetric synthesis of propargylic alcohols catalyzed by (-)-MITH

Ping Yu Wu, Hsyueh-Liang Wu, Ying Ying Shen, Biing Jiun Uang

Research output: Contribution to journalArticle

19 Citations (Scopus)

Abstract

This investigation describes that in the presence of 2.5 mol % of (-)-2-exo-morpholinoisobornane-10-thiol (MITH) 1, catalytic asymmetric alkynylation of aldehydes gives enantioenriched propargylic alcohols with good enantioselectivities.

Original languageEnglish
Pages (from-to)1837-1841
Number of pages5
JournalTetrahedron Asymmetry
Volume20
Issue number16
DOIs
Publication statusPublished - 2009 Aug 26

ASJC Scopus subject areas

  • Catalysis
  • Physical and Theoretical Chemistry
  • Organic Chemistry
  • Inorganic Chemistry

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