Asymmetric synthesis of propargylic alcohols catalyzed by (-)-MITH

Ping Yu Wu, Hsyueh-Liang Wu, Ying Ying Shen, Biing Jiun Uang

Research output: Contribution to journalArticle

19 Citations (Scopus)

Abstract

This investigation describes that in the presence of 2.5 mol % of (-)-2-exo-morpholinoisobornane-10-thiol (MITH) 1, catalytic asymmetric alkynylation of aldehydes gives enantioenriched propargylic alcohols with good enantioselectivities.

Original languageEnglish
Pages (from-to)1837-1841
Number of pages5
JournalTetrahedron Asymmetry
Volume20
Issue number16
DOIs
Publication statusPublished - 2009 Aug 26

Fingerprint

Enantioselectivity
Aldehydes
aldehydes
Sulfhydryl Compounds
thiols
alcohols
Alcohols
synthesis

ASJC Scopus subject areas

  • Catalysis
  • Physical and Theoretical Chemistry
  • Organic Chemistry
  • Inorganic Chemistry

Cite this

Asymmetric synthesis of propargylic alcohols catalyzed by (-)-MITH. / Wu, Ping Yu; Wu, Hsyueh-Liang; Shen, Ying Ying; Uang, Biing Jiun.

In: Tetrahedron Asymmetry, Vol. 20, No. 16, 26.08.2009, p. 1837-1841.

Research output: Contribution to journalArticle

Wu, Ping Yu ; Wu, Hsyueh-Liang ; Shen, Ying Ying ; Uang, Biing Jiun. / Asymmetric synthesis of propargylic alcohols catalyzed by (-)-MITH. In: Tetrahedron Asymmetry. 2009 ; Vol. 20, No. 16. pp. 1837-1841.
@article{4faaff4f30fb47dcbeb506286e7327d5,
title = "Asymmetric synthesis of propargylic alcohols catalyzed by (-)-MITH",
abstract = "This investigation describes that in the presence of 2.5 mol {\%} of (-)-2-exo-morpholinoisobornane-10-thiol (MITH) 1, catalytic asymmetric alkynylation of aldehydes gives enantioenriched propargylic alcohols with good enantioselectivities.",
author = "Wu, {Ping Yu} and Hsyueh-Liang Wu and Shen, {Ying Ying} and Uang, {Biing Jiun}",
year = "2009",
month = "8",
day = "26",
doi = "10.1016/j.tetasy.2009.07.032",
language = "English",
volume = "20",
pages = "1837--1841",
journal = "Tetrahedron Asymmetry",
issn = "0957-4166",
publisher = "Elsevier Limited",
number = "16",

}

TY - JOUR

T1 - Asymmetric synthesis of propargylic alcohols catalyzed by (-)-MITH

AU - Wu, Ping Yu

AU - Wu, Hsyueh-Liang

AU - Shen, Ying Ying

AU - Uang, Biing Jiun

PY - 2009/8/26

Y1 - 2009/8/26

N2 - This investigation describes that in the presence of 2.5 mol % of (-)-2-exo-morpholinoisobornane-10-thiol (MITH) 1, catalytic asymmetric alkynylation of aldehydes gives enantioenriched propargylic alcohols with good enantioselectivities.

AB - This investigation describes that in the presence of 2.5 mol % of (-)-2-exo-morpholinoisobornane-10-thiol (MITH) 1, catalytic asymmetric alkynylation of aldehydes gives enantioenriched propargylic alcohols with good enantioselectivities.

UR - http://www.scopus.com/inward/record.url?scp=69749128177&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=69749128177&partnerID=8YFLogxK

U2 - 10.1016/j.tetasy.2009.07.032

DO - 10.1016/j.tetasy.2009.07.032

M3 - Article

AN - SCOPUS:69749128177

VL - 20

SP - 1837

EP - 1841

JO - Tetrahedron Asymmetry

JF - Tetrahedron Asymmetry

SN - 0957-4166

IS - 16

ER -